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Role oflac repressor hinge region and operator DNA sequence in complex formation
A study of the lac repressor hinge region was undertaken to decipher its role in the function of DNA binding and communication between binding sites within the protein. Specific mutations were designed, and the proteins ...
Additional insights into the structure and function of adenosine deaminase
Adenosine deaminase is a key enzyme in purine catabolism. The elucidation of the crystal structure and recent analysis of site-directed mutants have provided details on the structure and function of the enzyme. The studies ...