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dc.contributor.authorRinaldi, Mauro A.
Liu, James
Enders, Tara A.
Bartel, Bonnie
Strader, Lucia C.
dc.date.accessioned 2015-01-06T15:49:13Z
dc.date.available 2015-01-06T15:49:13Z
dc.date.issued 2012
dc.identifier.citation Rinaldi, Mauro A., Liu, James, Enders, Tara A., et al.. "A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility." Plant Molecular Biology, 79, no. 4-5 (2012) 359-373. http://dx.doi.org/10.1007/s11103-012-9917-y.
dc.identifier.urihttps://hdl.handle.net/1911/78887
dc.description.abstract Auxin regulates many aspects of plant development, in part, through degradation of the Aux/IAA family of transcriptional repressors. Consequently, stabilizing mutations in several Aux/IAA proteins confer reduced auxin responsiveness. However, of the 29 apparent Aux/IAA proteins in Arabidopsis thaliana, fewer than half have roles established through mutant analysis. We identified iaa16-1, a dominant gain-of-function mutation in IAA16 (At3g04730), in a novel screen for reduced root responsiveness to abscisic acid. The iaa16-1 mutation also confers dramatically reduced auxin responses in a variety of assays, markedly restricts growth of adult plants, and abolishes fertility when homozygous. We compared iaa16-1 phenotypes with those of dominant mutants defective in the closely related IAA7/AXR2, IAA14/SLR, and IAA17/AXR3, along with the more distantly related IAA28, and found overlapping but distinct patterns of developmental defects. The identification and characterization of iaa16-1 provides a fuller understanding of the IAA7/IAA14/IAA16/IAA17 clade of Aux/IAA proteins and the diverse roles of these repressors in hormone response and plant development.
dc.language.iso eng
dc.rights This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Springer.
dc.title A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility
dc.type Journal article
dc.contributor.funder National Institutes of Health
dc.contributor.funder National Science Foundation
dc.contributor.funder Welch Foundation
dc.citation.journalTitle Plant Molecular Biology
dc.subject.keywordauxin signaling
abscisic acid
Aux/IAA gain of function
IAA16
dc.citation.volumeNumber 79
dc.citation.issueNumber 4-5
dc.contributor.publisher Springer
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1007/s11103-012-9917-y
dc.identifier.pmcid PMC3382072
dc.identifier.pmid 22580954
dc.identifier.grantID R00 GM089987-03 (National Institutes of Health)
dc.identifier.grantID MCB-0745122 (National Science Foundation)
dc.identifier.grantID C-1309 (Welch Foundation)
dc.type.publication post-print
dc.citation.firstpage 359
dc.citation.lastpage 373


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