Now showing items 11-20 of 205
Bayesian Inference of Reticulate Phylogenies under the Multispecies Network Coalescent
(Public Library of Science, 2016)
The multispecies coalescent (MSC) is a statistical framework that models how gene genealogies grow within the branches of a species tree. The field of computational phylogenetics has witnessed an explosion in the development ...
FlowCal: A User-Friendly, Open Source Software Tool for Automatically Converting Flow Cytometry Data from Arbitrary to Calibrated Units
(American Chemical Society, 2016)
Flow cytometry is widely used to measure gene expression and other molecular biological processes with single cell resolution via fluorescent probes. Flow cytometers output data in arbitrary units (a.u.) that vary with the ...
OVOL guides the epithelial-hybrid-mesenchymal transition
(Impact Journals, LLC, 2015)
Metastasis involves multiple cycles of Epithelial-to-Mesenchymal Transition (EMT) and its reverse-MET. Cells can also undergo partial transitions to attain a hybrid epithelial/mesenchymal (E/M) phenotype that has maximum ...
MUC1 stimulates EGFR expression and function in endometrial cancer
(Impact Journals, LLC, 2016)
The current standard of care for endometrial cancer patients involves hysterectomy with adjuvant radiation and chemotherapy, with no effective treatment for advanced and metastatic disease. MUC1 is a large, heavily ...
Tolerance of a Knotted Near-Infrared Fluorescent Protein to Random Circular Permutation
(American Chemical Society, 2016)
Environmental DNA (eDNA) detects the invasive crayfishes Orconectes rusticus and Pacifastacus leniusculus in large lakes of North America
We report results of a study that made reciprocal comparisons of environmental DNA (eDNA) assays for two major invasive crayfishes between their disparate invasive ranges in North America. Specifically, we tested for range ...
Shared Escovopsis parasites between leaf-cutting and non-leaf-cutting ants in the higher attine fungus-growing ant symbiosis
(Royal Society, 2015)
Fungus-gardening (attine) ants grow fungus for food in protected gardens, which contain beneficial, auxiliary microbes, but also microbes harmful to gardens. Among these potentially pathogenic microorganisms, the most ...
Vertebrate seed dispersers maintain the composition of tropical forest seedbanks
(Oxford University Press, 2015)
The accumulation of seeds in the soil (the seedbank) can set the template for the early regeneration of habitats following disturbance. Seed dispersal is an important factor determining the pattern of seed rain, which ...
Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA–DNA pairing
(Oxford University Press, 2016)
Proper chromosome alignment and segregation during mitosis depend on cohesion between sister chromatids. Cohesion is thought to occur through the entrapment of DNA within the tripartite ring (Smc1, Smc3 and Rad21) with ...
Combining Random Gene Fission and Rational Gene Fusion To Discover Near-Infrared Fluorescent Protein Fragments That Report on Protein–Protein Interactions
(American Chemical Society, 2015)
Gene fission can convert monomeric proteins into two-piece catalysts, reporters, and transcription factors for systems and synthetic biology. However, some proteins can be challenging to fragment without disrupting function, ...