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A pex1 missense mutation improves peroxisome function in a subset of Arabidopsis pex6 mutants without restoring PEX5 recycling
(National Academy of Sciences, 2018)
Peroxisomes are eukaryotic organelles critical for plant and human development because they house essential metabolic functions, such as fatty acid β-oxidation. The interacting ATPases PEX1 and PEX6 contribute to peroxisome ...
Pexophagy and peroxisomal protein turnover in plants
Peroxisomes are dynamic, vital organelles that sequester a variety of oxidative reactions and their toxic byproducts from the remainder of the cell. The oxidative nature of peroxisomal metabolism predisposes the organelle ...
Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy
(Landes Bioscience, 2014)
Peroxisomes are critical organelles housing various, often oxidative, reactions. Pexophagy, the process by which peroxisomes are selectively targeted for destruction via autophagy, is characterized in yeast and mammals but ...
A facile forward-genetic screen forﾠArabidopsisﾠautophagy mutants reveals twenty-one loss-of-function mutations disrupting sixﾠATGﾠgenes
(Taylor & Francis, 2019)
Macroautophagy is a process through which eukaryotic cells degrade large substrates including organelles, protein aggregates, and invading pathogens. Over 40 autophagy-related (ATG) genes have been identified through ...