Now showing items 1-3 of 3
Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling
(The Royal Society, 2017)
Epithelial–mesenchymal transition (EMT) plays key roles during embryonic development, wound healing and cancer metastasis. Cells in a partial EMT or hybrid epithelial/mesenchymal (E/M) phenotype exhibit collective cell ...
Interrogating the topological robustness of gene regulatory circuits by randomization
(Public Library of Science, 2017)
One of the most important roles of cells is performing their cellular tasks properly for survival. Cells usually achieve robust functionality, for example, cell-fate decision-making and signal transduction, through multiple ...
Distinguishing mechanisms underlying EMT tristability
(Springer International Publishing, 2017)
Abstract Background The Epithelial-Mesenchymal Transition (EMT) endows epithelial-looking cells with enhanced migratory ability during embryonic development and tissue ...