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dc.contributor.authorZheng, Wenj
Tao, Yizhi Jane
dc.date.accessioned 2014-10-06T17:18:00Z
dc.date.available 2014-10-06T17:18:00Z
dc.date.issued 2013
dc.identifier.citation Zheng, Wenj and Tao, Yizhi Jane. "Structure and assembly of the influenza A virus ribonucleoprotein complex." FEBS Letters, 587, no. 8 (2013) Elsevier: 1206-1214. http://dx.doi.org/10.1016/j.febslet.2013.02.048.
dc.identifier.urihttps://hdl.handle.net/1911/77394
dc.description.abstract The genome of influenza A viruses consists of eight segments of single-stranded, negative-sense RNA that are encapsidated as individual rod-shaped ribonucleoprotein complexes (RNPs). Each RNP contains a viral RNA, a viral polymerase and multiple copies of the viral nucleoprotein (NP). Influenza A virus RNPs play important roles during virus infection by directing viral RNA replication and transcription, intracellular transport of the viral RNA, gene reassortment as well as viral genome packaging into progeny particles. As a unique genomic entity, the influenza A virus RNP has been extensively studied since the 1960s. Recently, exciting progress has been made in studying the RNP structure and its assembly, leading to a better understanding of the structural basis of various RNP functions.
dc.language.iso eng
dc.publisher Elsevier
dc.rights This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/
dc.title Structure and assembly of the influenza A virus ribonucleoprotein complex
dc.type Journal article
dc.contributor.funder National Institutes of Health
dc.contributor.funder Welch Foundation
dc.citation.journalTitle FEBS Letters
dc.subject.keywordInfluenza A virus
Ribonucleoprotein complex
RNP
nucleoprotein
NP
structure
assembly
dc.citation.volumeNumber 587
dc.citation.issueNumber 8
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1016/j.febslet.2013.02.048
dc.identifier.pmid 23499938
dc.identifier.grantID AI077785 (National Institutes of Health)
dc.identifier.grantID C-1565 (Welch Foundation)
dc.type.publication publisher version
dc.citation.firstpage 1206
dc.citation.lastpage 1214


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