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dc.contributor.authorZimmermann, Juliane
Hayes, Ryan L.
Basan, Markus
Onuchic, José N..
Rappel, Wouter-Jan
Levine, Herbert
dc.date.accessioned 2014-09-09T16:04:21Z
dc.date.available 2014-09-09T16:04:21Z
dc.date.issued 2014
dc.identifier.citation Zimmermann, Juliane, Hayes, Ryan L., Basan, Markus, et al.. "Intercellular Stress Reconstitution from Traction Force Data." Biophysical Journal, 107, no. 3 (2014) 548-554. http://dx.doi.org/10.1016/j.bpj.2014.06.036.
dc.identifier.urihttps://hdl.handle.net/1911/77153
dc.description.abstract Cells migrate collectively during development, wound healing, and cancer metastasis. Recently, a method has been developed to recover intercellular stress in monolayers from measured traction forces upon the substrate. To calculate stress maps in two dimensions, the cell sheet was assumed to behave like an elastic material, and it remains unclear to what extent this assumption is valid. In this study, we simulate our recently developed model for collective cell migration, and compute intercellular stress maps using the method employed in the experiments. We also compute these maps using a method that does not depend on the traction forces or material properties. The two independently obtained stress patterns agree well for the parameters we have probed and provide a verification of the validity of the experimental method.
dc.language.iso eng
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.title Intercellular Stress Reconstitution from Traction Force Data
dc.type Journal article
dc.contributor.funder National Science Foundation
dc.contributor.funder Cancer Prevention and Research Institute of Texas
dc.citation.journalTitle Biophysical Journal
dc.contributor.org Center for Theoretical Biological Physics
dc.citation.volumeNumber 107
dc.citation.issueNumber 3
dc.contributor.publisher Elsevier
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1016/j.bpj.2014.06.036
dc.identifier.pmcid PMC4129476
dc.identifier.pmid 25099794
dc.identifier.grantID DMS-1068869 (National Science Foundation)
dc.identifier.grantID PHY-1308264 (National Science Foundation)
dc.type.publication publisher version
dc.citation.firstpage 548
dc.citation.lastpage 554


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