Show simple item record

dc.contributor.authorByrom, Julie
Han, Patric
Savory, Michael
Biswal, Sibani Lisa
dc.date.accessioned 2014-08-14T16:31:43Z
dc.date.available 2014-08-14T16:31:43Z
dc.date.issued 2014
dc.identifier.citation Byrom, Julie, Han, Patric, Savory, Michael, et al.. "Directing Assembly of DNA-Coated Colloids with Magnetic Fields To Generate Rigid, Semiflexible, and Flexible Chains." Langmuir, 30, no. 30 (2014) American Chemical Society: 9045-9052. http://dx.doi.org/10.1021/la5009939.
dc.identifier.urihttps://hdl.handle.net/1911/76515
dc.description.abstract We report the formation of colloidal macromolecules consisting of chains of micron-sized paramagnetic particles assembled using a magnetic field and linked with DNA. The interparticle spacing and chain flexibility were controlled by varying the magnetic field strength and the linker spring constant. Variations in the DNA lengths allowed for the generation of chains with an improved range of flexibility as compared to previous studies. These chains adopted the rigid-rod, semiflexible, and flexible conformations that are characteristic of linear polymer systems. These assembly techniques were investigated to determine the effects of the nanoscale DNA linker properties on the properties of the microscale colloidal chains. With stiff DNA linkers (564 base pairs) the chains were only stable at moderate to high field strengths and produced rigid chains. For flexible DNA linkers (8000 base pairs), high magnetic field strengths caused the linkers to be excluded from the gap between the particles, leading to a transition from very flexible chains at low field strengths to semiflexible chains at high field strengths. In the intermediate range of linker sizes, the chains exhibited predictable behavior, demonstrating increased flexibility with longer DNA linker length or smaller linking field strengths. This study provides insight into the process of directed assembly using magnetic fields and DNA by precisely tuning the components to generate colloidal analogues of linear macromolecular chains.
dc.language.iso eng
dc.publisher American Chemical Society
dc.rights This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society.
dc.title Directing Assembly of DNA-Coated Colloids with Magnetic Fields To Generate Rigid, Semiflexible, and Flexible Chains
dc.type Journal article
dc.contributor.funder National Science Foundation
dc.citation.journalTitle Langmuir
dc.citation.volumeNumber 30
dc.citation.issueNumber 30
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1021/la5009939
dc.identifier.pmid 25052952
dc.identifier.grantID CBET-0955003 (National Science Foundation)
dc.type.publication post-print
dc.citation.firstpage 9045
dc.citation.lastpage 9052


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record