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dc.contributor.authorWang, Yipeng
San, Ka-Yiu
Bennett, George N.
dc.date.accessioned 2014-02-14T21:19:55Z
dc.date.available 2014-02-14T21:19:55Z
dc.date.issued 2013
dc.identifier.citation Wang, Yipeng, San, Ka-Yiu and Bennett, George N.. "Cofactor engineering for advancing chemical biotechnology." Current Opinion in Biotechnology, 24, (2013) Elsevier: 994-999. http://dx.doi.org/10.1016/j.copbio.2013.03.022.
dc.identifier.urihttps://hdl.handle.net/1911/75475
dc.description.abstract Cofactors provide redox carriers for biosynthetic reactions, catabolic reactions and act as important agents in transfer of energy for the cell. Recent advances in manipulating cofactors include culture conditions or additive alterations, genetic modification of host pathways for increased availability of desired cofactor, changes in enzyme cofactor specificity, and introduction of novel redox partners to form effective circuits for biochemical processes and biocatalysts. Genetic strategies to employ ferredoxin, NADH and NADPH most effectively in natural or novel pathways have improved yield and efficiency of large-scale processes for fuels and chemicals and have been demonstrated with a variety of microbial organisms.
dc.language.iso eng
dc.publisher Elsevier
dc.rights This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.
dc.title Cofactor engineering for advancing chemical biotechnology
dc.type Journal article
dc.contributor.funder National Science Foundation
dc.citation.journalTitle Current Opinion in Biotechnology
dc.citation.volumeNumber 24
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1016/j.copbio.2013.03.022
dc.identifier.pmid 23611567
dc.identifier.grantID CBET-0828516 (National Science Foundation)
dc.identifier.grantID CBET-1033552 (National Science Foundation)
dc.type.publication post-print
dc.citation.firstpage 994
dc.citation.lastpage 999


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