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    Cofactor engineering for advancing chemical biotechnology

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    Author
    Wang, Yipeng; San, Ka-Yiu; Bennett, George N.
    Date
    2013
    Abstract
    Cofactors provide redox carriers for biosynthetic reactions, catabolic reactions and act as important agents in transfer of energy for the cell. Recent advances in manipulating cofactors include culture conditions or additive alterations, genetic modification of host pathways for increased availability of desired cofactor, changes in enzyme cofactor specificity, and introduction of novel redox partners to form effective circuits for biochemical processes and biocatalysts. Genetic strategies to employ ferredoxin, NADH and NADPH most effectively in natural or novel pathways have improved yield and efficiency of large-scale processes for fuels and chemicals and have been demonstrated with a variety of microbial organisms.
    Citation
    Wang, Yipeng, San, Ka-Yiu and Bennett, George N.. "Cofactor engineering for advancing chemical biotechnology." Current Opinion in Biotechnology, 24, (2013) Elsevier: 994-999. http://dx.doi.org/10.1016/j.copbio.2013.03.022.
    Published Version
    http://dx.doi.org/10.1016/j.copbio.2013.03.022
    Type
    Journal article
    Publisher
    Elsevier
    Citable link to this page
    https://hdl.handle.net/1911/75475
    Rights
    This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.
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    • Biochemistry and Cell Biology Publications [118]
    • Bioengineering Publications [632]
    • Chemical and Biomolecular Engineering Publications [253]
    • Faculty Publications [4988]

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    Home | FAQ | Contact Us | Privacy Notice | Accessibility Statement
    Managed by the Digital Scholarship Services at Fondren Library, Rice University
    Physical Address: 6100 Main Street, Houston, Texas 77005
    Mailing Address: MS-44, P.O.BOX 1892, Houston, Texas 77251-1892
    Site Map