Now showing items 21-40 of 4635

    • A framework to identify structured behavioral patterns within rodent spatial trajectories 

      Donnarumma, Francesco; Prevete, Roberto; Maisto, Domenico; Fuscone, Simone; Irvine, Emily M.; (2021)
      Animal behavior is highly structured. Yet, structured behavioral patterns—or “statistical ethograms”—are not immediately apparent from the full spatiotemporal data that behavioral scientists usually collect. Here, we introduce a framework to quantitatively characterize rodent behavior during spatial (e.g., maze) navigation, in terms of movement ...
    • Development, characterization, and applications of multi-material stereolithography bioprinting 

      Grigoryan, Bagrat; Sazer, Daniel W.; Avila, Amanda; Albritton, Jacob L.; Padhye, Aparna; (2021)
      As a 3D bioprinting technique, hydrogel stereolithography has historically been limited in its ability to capture the spatial heterogeneity that permeates mammalian tissues and dictates structure–function relationships. This limitation stems directly from the difficulty of preventing unwanted material mixing when switching between different liquid ...
    • Metal-to-insulator transition in Pt-doped TiSe 2 driven by emergent network of narrow transport channels 

      Lee, Kyungmin; Choe, Jesse; Iaia, Davide; Li, Juqiang; Zhao, Junjing; (2021)
      Metal-to-insulator transitions (MIT) can be driven by a number of different mechanisms, each resulting in a different type of insulator—Change in chemical potential can induce a transition from a metal to a band insulator; strong correlations can drive a metal into a Mott insulator with an energy gap; an Anderson transition, on the other hand, due ...
    • Novel Immune Modulators Enhance Caenorhabditis elegans Resistance to Multiple Pathogens 

      Hummell, Nicholas A.; Revtovich, Alexey V.; Kirienko, Natalia V. (2021)
      Traditionally, treatments for bacterial infection have focused on killing the microbe or preventing its growth. As antimicrobial resistance becomes more ubiquitous, the feasibility of this approach is beginning to wane and attention has begun to shift toward disrupting the host-pathogen interaction by improving the host defense. Using a high-throughput, ...
    • Groundwater Remediation of Volatile Organic Compounds Using Nanofiltration and Reverse Osmosis Membranes—A Field Study 

      Ainscough, Thomas J.; Oatley-Radcliffe, Darren L.; Barron, Andrew R. (2021)
      Groundwater contamination by chlorinated hydrocarbons represents a particularly difficult separation to achieve and very little is published on the subject. In this paper, we explore the potential for the removal of chlorinated volatile and non-volatile organics from a site in Bedfordshire UK. The compounds of interest include trichloroethylene (TCE), ...
    • The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells 

      Sharma, Rajiv; Dever, Daniel P.; Lee, Ciaran M.; Azizi, Armon; Pan, Yidan; (2021)
      Targeted DNA correction of disease-causing mutations in hematopoietic stem and progenitor cells (HSPCs) may enable the treatment of genetic diseases of the blood and immune system. It is now possible to correct mutations at high frequencies in HSPCs by combining CRISPR/Cas9 with homologous DNA donors. Because of the precision of gene correction, these ...
    • How Well Do Commonly Used Co-contraction Indices Approximate Lower Limb Joint Stiffness Trends During Gait for Individuals Post-stroke? 

      Li, Geng; Shourijeh, Mohammad S.; Ao, Di; Patten, Carolynn; Fregly, Benjamin J.; (2021)
      Muscle co-contraction generates joint stiffness to improve stability and accuracy during limb movement but at the expense of higher energetic cost. However, quantification of joint stiffness is difficult using either experimental or computational means. In contrast, quantification of muscle co-contraction using an EMG-based Co-Contraction Index (CCI) ...
    • Overlaid positive and negative feedback loops shape dynamical properties of PhoPQ two-component system 

      Rao, Satyajit D.; Igoshin, Oleg A.; Center for Theoretical Biological Physics (2021)
      Bacteria use two-component systems (TCSs) to sense environmental conditions and change gene expression in response to those conditions. To amplify cellular responses, many bacterial TCSs are under positive feedback control, i.e. increase their expression when activated. Escherichia coli Mg2+ -sensing TCS, PhoPQ, in addition to the positive feedback, ...
    • Highly efficient photoelectric effect in halide perovskites for regenerative electron sources 

      Liu, Fangze; Sidhik, Siraj; Hoffbauer, Mark A.; Lewis, Sina; Neukirch, Amanda J.; (2021)
      Electron sources are a critical component in a wide range of applications such as electron-beam accelerator facilities, photomultipliers, and image intensifiers for night vision. We report efficient, regenerative and low-cost electron sources based on solution-processed halide perovskites thin films when they are excited with light with energy equal ...
    • Reconciling bubble nucleation in explosive eruptions with geospeedometers 

      Hajimirza, Sahand; Gonnermann, Helge M.; Gardner, James E. (2021)
      Magma from Plinian volcanic eruptions contains an extraordinarily large numbers of bubbles. Nucleation of those bubbles occurs because pressure decreases as magma rises to the surface. As a consequence, dissolved magmatic volatiles, such as water, become supersaturated and cause bubbles to nucleate. At the same time, diffusion of volatiles into ...
    • Stable isotope (C, N, O, and H) study of a comprehensive set of feathers from two Setophaga citrina 

      Deme, Samiksha; Yeung, Laurence Y.; Sun, Tao; Lee, Cin-Ty A. (2021)
      Oxygen, hydrogen, carbon and nitrogen stable isotopes were measured on a comprehensive sampling of feathers from two spring Hooded Warblers (Setophaga citrina) in Texas to evaluate isotopic variability between feathers and during molt. Isotopic homogeneity within each bird was found across all four isotopic systems, supporting the hypothesis that ...
    • Search for dark matter produced in association with a leptonically decaying Z boson in proton–proton collisions at s√=13TeV 

      CMS Collaboration (2021)
      A search for dark matter particles is performed using events with a Z boson candidate and large missing transverse momentum. The analysis is based on proton–proton collision data at a center-of-mass energy of 13TeV, collected by the CMS experiment at the LHC in 2016–2018, corresponding to an integrated luminosity of 137fb−1. The search uses the decay ...
    • Search for the lepton flavor violating decay τ → 3μ in proton-proton collisions at s√= 13 TeV 

      The CMS collaboration (2021)
      Results are reported from a search for the lepton flavor violating decay τ → 3μ in proton-proton collisions at s√ = 13 TeV. The data sample corresponds to an integrated luminosity of 33.2 fb−1 recorded by the CMS experiment at the LHC in 2016. The search exploits τ leptons produced in both W boson and heavy-flavor hadron decays. No significant excess ...
    • Study of the normalized transverse momentum distribution of W bosons produced in p¯p collisions at √s=1.96  TeV 

      The D0 Collaboration (2021)
      We present a study of the normalized transverse momentum distribution of W bosons produced in p¯p collisions, using data corresponding to an integrated luminosity of 4.35 fb−1 collected with the D0 detector at the Fermilab Tevatron collider at √s=1.96 TeV. The measurement focuses on the transverse momentum region below 15 GeV, which is of special ...
    • Spectral Properties of Effective Dynamics from Conditional Expectations 

      Nüske, Feliks; Koltai, Péter; Boninsegna, Lorenzo; Clementi, Cecilia; Center for Theoretical Biological Physics (2021)
      The reduction of high-dimensional systems to effective models on a smaller set of variables is an essential task in many areas of science. For stochastic dynamics governed by diffusion processes, a general procedure to find effective equations is the conditioning approach. In this paper, we are interested in the spectrum of the generator of the ...
    • Phonon-Assisted Hot Carrier Generation in Plasmonic Semiconductor Systems 

      Hattori, Yocefu; Meng, Jie; Zheng, Kaibo; Meier de Andrade, Ageo; Kullgren, Jolla; (2021)
      Plasmonic materials have optical cross sections that exceed by 10-fold their geometric sizes, making them uniquely suitable to convert light into electrical charges. Harvesting plasmon-generated hot carriers is of interest for the broad fields of photovoltaics and photocatalysis; however, their direct utilization is limited by their ultrafast ...
    • Nanoscale Probing of Image-Potential States and Electron Transfer Doping in Borophene Polymorphs 

      Liu, Xiaolong; Wang, Luqing; Yakobson, Boris I.; Hersam, Mark C. (2021)
      Because synthetic 2D materials are generally stabilized by interfacial coupling to growth substrates, direct probing of interfacial phenomena is critical for understanding their nanoscale structure and properties. Using field-emission resonance spectroscopy with an ultrahigh vacuum scanning tunneling microscope, we reveal Stark-shifted image-potential ...
    • Robust Multiple Regression 

      Scott, David W.; Wang, Zhipeng (2021)
      As modern data analysis pushes the boundaries of classical statistics, it is timely to reexamine alternate approaches to dealing with outliers in multiple regression. As sample sizes and the number of predictors increase, interactive methodology becomes less effective. Likewise, with limited understanding of the underlying contamination process, ...
    • Evidence for Higgs boson decay to a pair of muons 

      The CMS collaboration (2021)
      Evidence for Higgs boson decay to a pair of muons is presented. This result combines searches in four exclusive categories targeting the production of the Higgs boson via gluon fusion, via vector boson fusion, in association with a vector boson, and in association with a top quark-antiquark pair. The analysis is performed using proton-proton collision ...
    • Measurements of production cross sections of polarized same-sign W boson pairs in association with two jets in proton-proton collisions at s=13 TeV 

      The CMS Collaboration (2021)
      The first measurements of production cross sections of polarized same-sign W±W± boson pairs in proton-proton collisions are reported. The measurements are based on a data sample collected with the CMS detector at the LHC at a center-of-mass energy of 13TeV, corresponding to an integrated luminosity of 137fb−1. Events are selected by requiring exactly ...