Now showing items 3775-3794 of 5118

    • Sabertooth carcass consumption behavior and the dynamics of Pleistocene large carnivoran guilds 

      Domínguez-Rodrigo, Manuel; Egeland, Charles P.; Cobo-Sánchez, Lucía; Baquedano, Enrique; Hulbert, Richard C. (2022)
      Apex predators play an important role in the top-down regulation of ecological communities. Their hunting and feeding behaviors influence, respectively, prey demography and the availability of resources to other consumers. Among the most iconic—and enigmatic—terrestrial predators of the late Cenozoic are the Machairodontinae, a diverse group of big ...
    • Salivary biomarkers associated with myocardial necrosis: results from an alcohol septal ablation model 

      Foley, Joseph D. III; Sneed, J. Darrell; Steinhubl, Steven R.; Kolasa, Justin R.; Ebersole, Jeffrey L.; (2012)
      Objective: To determine if salivary biomarkers demonstrate utility for identifying aspects of myocardial necrosis. Methods: Twenty-one patients undergoing alcohol septal ablation (ASA) for treatment of hypertrophic cardiomyopathy provided serum and unstimulated whole saliva at baseline and incremental time points post-ASA. Samples were analyzed for ...
    • Sample-to-answer, extraction-free, real-time RT-LAMP test for SARS-CoV-2 in nasopharyngeal, nasal, and saliva samples: Implications and use for surveillance testing 

      Kundrod, Kathryn A.; Natoli, Mary E.; Chang, Megan M.; Smith, Chelsey A.; Paul, Sai; (2022)
      The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected individuals. We optimized a sample-to-answer nucleic acid test for SARS-CoV-2 that provides results in <1 hour using inexpensive and readily available reagents. The test workflow includes a simple ...
    • Santa Barbara, Physics, and the Long 1970s 

      (2013-09)
      The adaptations of a group of Southern California physicists to the trying conditions of the 1970s anticipated some of the important 21st-century trends in the discipline.
    • SARS-Arena: Sequence and Structure-Guided Selection of Conserved Peptides from SARS-related Coronaviruses for Novel Vaccine Development 

      Rigo, Mauricio Menegatti; Fasoulis, Romanos; Conev, Anja; Hall-Swan, Sarah; Antunes, Dinler Amaral; (2022)
      The pandemic caused by the SARS-CoV-2 virus, the agent responsible for the COVID-19 disease, has affected millions of people worldwide. There is constant search for new therapies to either prevent or mitigate the disease. Fortunately, we have observed the successful development of multiple vaccines. Most of them are focused on one viral envelope ...
    • SARS-CoV-2 genomic diversity and the implications for qRT-PCR diagnostics and transmission 

      Sapoval, Nicolae; Mahmoud, Medhat; Jochum, Michael D.; Liu, Yunxi; Elworth, R. A. Leo; (2021)
      The COVID-19 pandemic has sparked an urgent need to uncover the underlying biology of this devastating disease. Though RNA viruses mutate more rapidly than DNA viruses, there are a relatively small number of single nucleotide polymorphisms (SNPs) that differentiate the main SARS-CoV-2 lineages that have spread throughout the world. In this study, we ...
    • SAVI: Synthetic apertures for long-range, subdiffraction-limited visible imaging using Fourier ptychography 

      Holloway, Jason; Wu, Yicheng; Sharma, Manoj K.; Cossairt, Oliver; Veeraraghavan, Ashok (2017)
      Synthetic aperture radar is a well-known technique for improving resolution in radio imaging. Extending these synthetic aperture techniques to the visible light domain is not straightforward because optical receivers cannot measure phase information. We propose to use macroscopic Fourier ptychography (FP) as a practical means of creating a synthetic ...
    • Scaffolds to Control Inflammation and Facilitate Dental Pulp Regeneration 

      (2014)
      In dentistry, the maintenance of a vital dental pulp is of paramount importance because teeth devitalized by root canal treatment may become more brittle and prone to structural failure over time. Advanced carious lesions can irreversibly damage the dental pulp by propagating a sustained inflammatory response throughout the tissue. Although the ...
    • Scalable user selection in FDD massive MIMO 

      Zhang, Xing; Sabharwal, Ashutosh (2021)
      User subset selection requires full downlink channel state information to realize effective multi-user beamforming in frequency-division duplexing (FDD) massive multi-input multi-output (MIMO) systems. However, the channel estimation overhead scales with the number of users in FDD systems. In this paper, we propose a novel propagation domain-based ...
    • Scaled laboratory experiments explain the kink behaviour of the Crab Nebula jet 

      Li, C.K.; Tzeferacos, P.; Lamb, D.; Gregori, G.; Norreys, P.A.; (2016)
      The remarkable discovery by the Chandra X-ray observatory that the Crab nebulaメs jet periodically changes direction provides a challenge to our understanding of astrophysical jet dynamics. It has been suggested that this phenomenon may be the consequence of magnetic fields and magnetohydrodynamic instabilities, but experimental demonstration in a ...
    • Scaling law for excitons in 2D perovskite quantum wells 

      Blancon, J.-C.; Stier, A.V.; Tsai, H.; Nie, W.; Stoumpos, C.C.; (2018)
      Ruddlesden-Popper halide perovskites are 2D solution-processed quantum wells with a general formula A2A'n-1M n X3n+1, where optoelectronic properties can be tuned by varying the perovskite layer thickness (n-value), and have recently emerged as efficient semiconductors with technologically relevant stability. However, fundamental questions concerning ...
    • Scaling of Relativistic Shear Flows with the Bulk Lorentz Factor 

      Liang, Edison; Fu, Wen; Böttcher, Markus; Roustazadeh, Parisa (2018)
      We compare Particle-in-cell simulation results of relativistic electron–ion shear flows with different bulk Lorentz factors, and discuss their implications for spine-sheath models of blazar versus gamma-ray burst (GRB) jets. Specifically, we find that most properties of the shear boundary layer scale with the bulk Lorentz factor: the lower the Lorentz ...
    • Scaling properties of the plateau transitions in the two-dimensional hole gas system 

      Wang, Xuebin; Liu, Haiwen; Zhu, Junbo; Shan, Pujia; Wang, Pengjie; (2016)
      The behavior of phase coherence is studied in two-dimensional hole gas through the integer quantum Hall plateau-to-plateau transition. From the plateau transition as a function of temperature, scaling properties of multiple transitions are analyzed. Our results are in good agreement with the assumption of the zero-point fluctuations of the coherent ...
    • Scaling relationships and physics for mixed heating convection in planetary interiors: Isoviscous spherical shells 

      Weller, Matthew B.; Lenardic, Adrian; Moore, William B.; Lunar and Planetary Institute (2016)
      We use a suite of 3-D numerical experiments to test and expand 2-D planar isoviscous scaling relationships of Moore (2008) for mixed heating convection in spherical geometry mantles over a range of Rayleigh numbers (Ra). The internal temperature scaling of Moore (2008), when modified to account for spherical geometry, matches our experimental results ...
    • Scaling Solution in the Large Population Limit of the General Asymmetric Stochastic Luria–Delbrück Evolution Process 

      Kessler, David A.; Levine, Herbert; Center for Theoretical Biological Physics (2015)
      One of the most popular models for quantitatively understanding the emergence of drug resistance both in bacterial colonies and in malignant tumors was introduced long ago by Luria and Delbrück. Here, individual resistant mutants emerge randomly during the birth events of an exponentially growing sensitive population. A most interesting limit of this ...
    • Scanning-Ion Microscopy with Polarization Analysis (Simpa) 

      Zheng, N.J.; Rau, C.; Rice Quantum Institute (1993)
      We have developed a novel, high-resolution magnetic imaging technique, scanning-ion microscopy with polarization analysis (SIMP A). In SIMP A, a highly-focused, scanning Ga+ ion beam is used to excite spin-polarized electrons at surfaces of ferromagnetic materials. By measuring the intensity and the spin polarization of the emitted electrons using a ...
    • Scattering and dip angle decomposition based on subsurface offset extended wave-equation migration 

      Dafni, Raanan; Symes, William W. (2016)
      An angle-dependent reflection coefficient is recovered by seismic migration in the angle domain. We have developed a postmigration technique for computing scattering and dip angle common-image gathers (CIGs) from seismic images, extended by the subsurface offset, based on wave-equation migration methods. Our methodology suggests a system of Radon ...
    • SCHEMA Computational Design of Virus Capsid Chimeras: Calibrating How Genome Packaging, Protection, and Transduction Correlate with Calculated Structural Disruption 

      Ho, Michelle L.; Adler, Benjamin A.; Torre, Michael L.; Silberg, Jonathan J.; Suh, Junghae (2013)
      Adeno-associated virus (AAV) recombination can result in chimeric capsid protein subunits whose ability to assemble into an oligomeric capsid, package a genome, and transduce cells depends on the inheritance of sequence from different AAV parents. To develop quantitative design principles for guiding site-directed recombination of AAV capsids, we ...