Now showing items 3503-3522 of 5118

    • Race and ethnic minority, local pollution, and COVID-19 deaths in Texas 

      Xu, Annie; Loch-Temzelides, Ted; Adiole, Chima; Botton, Nathan; Dee, Sylvia G.; (2022)
      The costs of COVID-19 are extensive, and, like the fallout of most health and environmental crises in the US, there is growing evidence that these costs weigh disproportionately on communities of color. We investigated whether county-level racial composition and fine particulate pollution (PM2.5) are indicators for COVID-19 incidence and death rates ...
    • Racial residential segregation shapes the relationship between early childhood lead exposure and fourth-grade standardized test scores 

      Bravo, Mercedes A.; Zephyr, Dominique; Kowal, Daniel; Ensor, Katherine; Miranda, Marie Lynn (2022)
      Racial/ethnic disparities in academic performance may result from a confluence of adverse exposures that arise from structural racism and accrue to specific subpopulations. This study investigates childhood lead exposure, racial residential segregation, and early educational outcomes. Geocoded North Carolina birth data is linked to blood lead ...
    • RACIPE: a computational tool for modeling gene regulatory circuits using randomization 

      Huang, Bin; Jia, Dongya; Feng, Jingchen; Levine, Herbert; Onuchic, José N.; (2018)
      BACKGROUND: One of the major challenges in traditional mathematical modeling of gene regulatory circuits is the insufficient knowledge of kinetic parameters. These parameters are often inferred from existing experimental data and/or educated guesses, which can be time-consuming and error-prone, especially for large networks. RESULTS: We present a ...
    • Radial Velocity Monitoring of the Young Star Hubble 4: Disentangling Star-spot Lifetimes from Orbital Motion 

      Carvalho, Adolfo; Johns-Krull, Christopher M.; Prato, L.; Anderson, Jay (2021)
      We studied the weak-lined T Tauri star Hubble 4, a known long-period binary, and its star-spot phenomena. We used optical radial velocity (RV) data taken over a span of 14 yr (2004–2010, 2017–2019) at the McDonald Observatory 2.7 m Harlan J. Smith Telescope and single epoch imaging from the Hubble Space Telescope (HST)/Wide Field Camera 3 instrument. ...
    • Radiation testing of electronics for the CMS endcap muon system 

      Bylsma, B.; Cady, D.; Celik, A.; Durkin, L.S.; Gilmore, J.; (2013)
      The electronics used in the data readout and triggering system for the Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) particle accelerator at CERN are exposed to high radiation levels. This radiation can cause permanent damage to the electronic circuitry, as well as temporary effects such as data corruption induced by Single ...
    • Radiation-Induced Cardiovascular Disease: Mechanisms and Importance of Linear Energy Transfer 

      Sylvester, Christopher B.; Abe, Jun-ichi; Patel, Zarana S.; Grande-Allen, K. Jane (2018)
      Radiation therapy (RT) in the form of photons and protons is a well-established treatment for cancer. More recently, heavy charged particles have been used to treat radioresistant and high-risk cancers. Radiation treatment is known to cause cardiovascular disease (CVD) which can occur acutely during treatment or years afterward in the form of accelerated ...
    • Radiative Decay Rates in Hg+ from Observations of Quantum Jumps in a Single Ion 

      Itano, Wayne M.; Bergquist, J.C.; Hulet, Randall G.; Wineland, D.J. (1987)
      Radiative decay rates connecting the lowest four energy levels of Hg+198 have been derived solely from an analysis of the fluctuations (quantum jumps) of the laser-induced fluorescence of the 194-nm first resonance transition of a single ion confined in a Paul trap. The natural linewidth of the 194-nm first resonance transition was also measured. The ...
    • Radiative lifetime of the 2P state of lithium 

      McAlexander, W.I.; Abraham, E.R.I.; Hulet, R.G.; Rice Quantum Institute (1996)
      We determine the radial dipole moment between the 2S and 2P states of atomic lithium by analyzing the long-range vibrational eigenenergies of the singly excited diatomic molecule. The result can be expressed in terms of the 2P12 radiative lifetime of Li7, which is found to be 27.102(2)(7) ns. This result agrees with most current atomic-structure ...
    • Radiometric and design model for the tunable light-guide image processing snapshot spectrometer (TuLIPSS) 

      Zheng, Desheng; Flynn, Christopher; Stoian, Razvan I.; Lu, Jiawei; Cao, Haimu; (2021)
      The tunable light-guide image processing snapshot spectrometer (TuLIPSS) is a novel remote sensing instrument that can capture a spectral image cube in a single snapshot. The optical modelling application for the absolute signal intensity on a single pixel of the sensor in TuLIPSS has been developed through a numerical simulation of the integral ...
    • Raman scattering study of NaFe0.53Cu0.47As 

      Zhang, W.-L.; Song, Y.; Wang, W.-Y.; Cao, C.-D.; Dai, P.-C.; (2018)
      We use polarization-resolved Raman scattering to study lattice dynamics in NaFe0.53Cu0.47As single crystals. We identify four A1g phonon modes, at 126, 172, 183, and 197 cm−1, and four B3g phonon modes at 101, 139, 173, and 226 cm−1(D4h point group). The phonon spectra are consistent with the Ibam space group, which confirms that the Cu and Fe atoms ...
    • Rampant Parasexuality Evolves in a Hospital Pathogen during Antibiotic Selection 

      (2015)
      Horizontal gene transfer threatens the therapeutic success of antibiotics by facilitating the rapid dissemination of resistance alleles among bacterial species. The conjugative mobile element Tn916 provides an excellent context for examining the role of adaptive parasexuality as it carries the tetracycline-resistance allele tetM and has been identified ...
    • Random Hamiltonians with arbitrary point interactions in one dimension 

      Damanik, David; Fillman, Jake; Helman, Mark; Kesten, Jacob; Sukhtaiev, Selim (2021)
      We consider disordered Hamiltonians given by the Laplace operator subject to arbitrary random self-adjoint singular perturbations supported on random discrete subsets of the real line. Under minimal assumptions on the type of disorder, we prove the following dichotomy: Either every realization of the random operator has purely absolutely continuous ...
    • Random Insertion of mCherry Into VP3 Domain of Adeno- associated Virus Yields Fluorescent Capsids With no Loss of Infectivity 

      Judd, Justin; Wei, Fang; Nguyen, Peter Q.; Tartaglia, Lawrence J.; Agbandje-McKenna, Mavis; (2012)
      Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to track vector transport. Unfortunately, rational approaches ...
    • Random Sturm-Liouville operators with generalized point interactions 

      Damanik, David; del Rio, Rafael; Franco, Asaf L. (2020)
      In this work we study the point spectra of selfadjoint Sturm-Liouville operators with generalized point interactions, where the two one-sided limits of the solution data are relatedvia a general SL(2,R)matrix. We are particularly interested in the stability of eigenvalues withrespect to the variation of the parameters of the interaction matrix. As a ...
    • Random Vibrations of Nonlinear Continua Endowed with Fractional Derivative Elements 

      Spanos, Pol D.; Malara, Giovanni (2017)
      In this paper, two techniques are proposed for determining the large displacement statistics of random exciting continua endowed with fractional derivative elements: Boundary Element Method (BEM) based Monte Carlo simulation; and Statistical Linearization (SL). The techniques are applied to the problem of nonlinear beam and plate random response ...
    • Range-Separated Brueckner Coupled Cluster Doubles Theory 

      Shepherd, James J.; Henderson, Thomas M.; Scuseria, Gustavo E. (2014)
      We introduce a range-separation approximation to coupled cluster doubles (CCD) theory that successfully overcomes limitations of regular CCD when applied to the uniform electron gas. We combine the short-range ladder channel with the long-range ring channel in the presence of a Bruckner renormalized one-body interaction and obtain ground-state energies ...
    • RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization 

      (2014)
      Prostate cancer (PCa) metastasis to bone is lethal and there is no adequate animal model to study the mechanisms underlying the metastatic process. Here we report that receptor activator of NF-κB ligand (RANKL) expressed by PCa cells consistently induced colonization or metastasis to bone in animal models. RANK-mediated signaling established a ...
    • A Rapid and Sensitive Method for Measuring NAcetylglucosaminidase Activity in Cultured Cells 

      (2013)
      A rapid and sensitive method to quantitatively assess N-acetylglucosaminidase (NAG) activity in cultured cells is highly desirable for both basic research and clinical studies. NAG activity is deficient in cells from patients with Mucopolysaccharidosis type IIIB (MPS IIIB) due to mutations in NAGLU, the gene that encodes NAG. Currently available techniques ...
    • Rapid Calculation of Molecular Kinetics Using Compressed Sensing 

      Litzinger, Florian; Boninsegna, Lorenzo; Wu, Hao; Nüske, Feliks; Patel, Raajen; (2018)
      Recent methods for the analysis of molecular kinetics from massive molecular dynamics (MD) data rely on the solution of very large eigenvalue problems. Here we build upon recent results from the field of compressed sensing and develop the spectral oASIS method, a highly efficient approach to approximate the leading eigenvalues and eigenvectors of ...
    • Rapid casting of patterned vascular networks for perfusable engineered 3D tissues 

      Miller, Jordan S.; Stevens, Kelly R.; Yang, Michael T.; Baker, Brendon M.; Nguyen, Duc-Huy T.; (2012)
      In the absence of perfusable vascular networks, three-dimensional (3D) engineered tissues densely populated with cells quickly develop a necrotic core [1]. Yet the lack of a general approach to rapidly construct such networks remains a major challenge for 3D tissue culture [2-4]. Here, we 3D printed rigid filament networks of carbohydrate glass, and ...