Now showing items 3160-3179 of 5118

    • P-Type Silicon Strip Sensors for the new CMS Tracker at HL-LHC 

      Tracker Group of the CMS Collaboration; Akgün, B.; Ecklund, K.M.; Kilpatrick, M.; Nussbaum, T.; (2017)
      The upgrade of the LHC to the High-Luminosity LHC (HL-LHC) is expected to increase the LHC design luminosity by an order of magnitude. This will require silicon tracking detectors with a significantly higher radiation hardness. The CMS Tracker Collaboration has conducted an irradiation and measurement campaign to identify suitable silicon sensor ...
    • p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines 

      Chang, Megan A.; Morgado, Micaela; Warren, Curtis R.; Hinton, Cimona V.; Farach-Carson, Mary C.; (2014)
      BACKGROUND: Bone marrow stromal cell (BMSC) paracrine factor(s) can induce apoptosis in bone metastatic prostate cancer (PCa) cell lines. However, the PCa cells that escape BMSC-induced apoptosis can upregulate cytoprotective autophagy. METHODS: C4-2, C4-2B, MDA PCa 2a, MDA PCa 2b, VCaP, PC3, or DU145 PCa cell lines were grown in BMSC conditioned ...
    • Pacific Plate Apparent Polar Wander, Hot Spot Fixity, and True Polar Wander During the Formation of the Hawaiian Island and Seamount Chain From an Analysis of the Skewness of Magnetic Anomaly 20r (44ᅠMa) 

      Zheng, Lin; Gordon, Richard G.; Woodworth, Daniel (2018)
      While it is well documented that the Hawaiian hot spot has shifted southward relative to the spin axis since the formation of some of the Emperor seamounts, the paleolatitude of the hot spot during the formation of the Hawaiian chain is poorly known. To better determine the latter, here we estimate the location of the 44 Ma Pacific plate paleomagnetic ...
    • Pacific plate deformation from horizontal thermal contraction 

      (2014)
      The central approximation of plate tectonics is that the plates are rigid, which gives the theory its rigor and predictive power. Space geodetic measurements are consistent with the rigidity of stable plate interiors, but some failures of plate-circuit closure, in particular of oceanic plates, indicate that plates may be measurably non-rigid. We ...
    • Paintable Battery 

      Singh, Neelam; Galande, Charudatta; Miranda, Andrea; Mathkar, Akshay; Gao, Wei; (2012)
      If the components of a battery, including electrodes, separator, electrolyte and the current collectors can be designed as paints and applied sequentially to build a complete battery, on any arbitrary surface, it would have significant impact on the design, implementation and integration of energy storage devices. Here, we establish a paradigm change ...
    • Pair extended coupled cluster doubles 

      Henderson, Thomas M.; Bulik, Ireneusz W.; Scuseria, Gustavo E. (2015)
      The accurate and efficient description of strongly correlated systems remains an important challenge for computational methods. Doubly occupied configuration interaction (DOCI), in which all electrons are paired and no correlations which break these pairs are permitted, can in many cases provide an accurate account of strong correlations, albeit at ...
    • Pairing and Phase Separation in a Polarized Fermi Gas 

      Partridge, Guthrie B.; Li, Wenhui; Kamar, Ramsey I.; Liao, Yean-an; Hulet, Randall G. (2006)
      We report the observation of pairing in a gas of atomic fermions with unequal numbers of two components. Beyond a critical polarization, the gas separates into a phase that is consistent with a superfluid paired core surrounded by a shell of normal unpaired fermions. The critical polarization diminishes with decreasing attractive interaction. For ...
    • Pairing correlations near a Kondo-destruction quantum critical point 

      Pixley, J.H.; Deng, Lili; Ingersent, Kevin; Si, Qimiao (2015)
      Motivated by the unconventional superconductivity observed in heavy-fermion metals, we investigate pairing susceptibilities near a continuous quantum phase transition of the Kondo-destruction type. We solve two-impurity Bose-Fermi Anderson models with Ising and Heisenberg forms of the interimpurity exchange interaction using continuous-time quantum ...
    • Palaeogenomic analysis of black rat (Rattus rattus) reveals multiple European introductions associated with human economic history 

      Yu, He; Jamieson, Alexandra; Hulme-Beaman, Ardern; Conroy, Chris J.; Knight, Becky; (2022)
      The distribution of the black rat (Rattus rattus) has been heavily influenced by its association with humans. The dispersal history of this non-native commensal rodent across Europe, however, remains poorly understood, and different introductions may have occurred during the Roman and medieval periods. Here, in order to reconstruct the population ...
    • Paleolatitude of the Hawaiian Hot Spot Since 48 Ma: Evidence for a Mid‐Cenozoic True Polar Stillstand Followed by Late Cenozoic True Polar Wander Coincident With Northern Hemisphere Glaciation 

      Woodworth, Daniel; Gordon, Richard G. (2018)
      Paleospin axis locations since 48 Ma inferred from the distribution of equatorial sediment accumulation rates on the Pacific plate, together with paleomagnetic poles from magnetic anomaly skewness, indicate that the Hawaiian hot spot was nearly fixed in latitude from 48 to 12 Ma, but ≈3° north of its current latitude. From 48 to 12 Ma in the Pacific ...
    • A paper and plastic device for performing recombinase polymerase amplification of HIV DNA 

      Rohrman, Brittany A.; Richards-Kortum, Rebecca R. (2012)
      Despite the importance of early diagnosis and treatment of HIV, only a small fraction of HIV-exposed infants in low- and middle-income countries are tested for the disease. The gold standard for early infant diagnosis, DNA PCR, requires resources that are unavailable in poor settings, and no point-of-care HIV DNA test is currently available. We have ...
    • Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay 

      Natoli, Mary E.; Rohrman, Brittany A.; De Santiago, Carolina; van Zyl, Gert U.; Richards-Kortum, Rebecca R. (2018)
      Regular HIV-1 viral load monitoring is the standard of care to assess antiretroviral therapy effectiveness in resource-rich settings. Persistently elevated viral loads indicate virologic failure (VF), which warrants HIV drug resistance testing (HIVDRT) to allow individualized regimen switches. However, in settings lacking access to HIVDRT, clinical ...
    • A paper-based immunoassay to determine HPV vaccination status at the point-of-care 

      Grant, Benjamin D.; Smith, Chelsey A.; Castle, Philip E.; Scheurer, Michael E.; Richards-Kortum, Rebecca (2016)
      Objective: To develop and evaluate a paper-based point-of-care HPV serology test to determine if an individual has received two or more HPV immunizations. Methods: The paper-based immunoassay was constructed using a nitrocellulose lateral flow strip with adsorbed HPV16 virus-like particles serving as the capturing moiety. Three capture zones containing ...
    • Paradoxical Infrastructures: Ruins, Retrofit, and Risk 

      Howe, Cymene; Lockrem, Jessica; Appel, Hannah; Hackett, Edward; Boyer, Dominic; (2015)
      In recent years, a dramatic increase in the study of infrastructure has occurred in the social sciences and humanities, following upon foundational work in the physical sciences, architecture, planning, information science, and engineering. This article, authored by a multidisciplinary group of scholars, probes the generative potential of infrastructure ...
    • Parallel bulk heterojunction photovoltaics based on all-conjugated block copolymer additives 

      Mok, Jorge W.; Kipp, Dylan; Hasbun, Luis R.; Dolocan, Andrei; Strzalka, Joseph; (2016)
      In recent studies, we demonstrated that the addition of block copolymers to binary donorヨacceptor blends represents an effective approach to target equilibrium, co-continuous morphologies of interpenetrating donors and acceptors. Here, we report a study of the impact of all-conjugated poly(thieno[3,4-b]-thiophene-co-benzodithiophene)-b-polynaphthalene ...
    • Parallel continuous simulated tempering and its applications in large-scale molecular simulations 

      Zang, Tianwu; Yu, Linglin; Zhang, Chong; Ma, Jianpeng (2014)
      In this paper, we introduce a parallel continuous simulated tempering (PCST) method for enhanced sampling in studying large complex systems. It mainly inherits the continuous simulated tempering (CST) method in our previous studies [C. Zhang and J. Ma, J. Chem. Phys. 130, 194112 (2009); C. Zhang and J. Ma, J. Chem. Phys. 132, 244101 (2010)], while ...
    • Parallel Digital Predistortion Design on Mobile GPU and Embedded Multicore CPU for Mobile Transmitters 

      Li, Kaipeng; Ghazi, Amanullah; Tarver, Chance; Juntti, Markku; Boutellier, Jani; (2017)
      Digital predistortion (DPD) is a widely adopted baseband processing technique in current radio transmitters. While DPD can effectively suppress unwanted spurious spectrum emissions stemming from imperfections of analog RF and baseband electronics, it also introduces extra processing complexity and poses challenges on efficient and flexible implementations, ...
    • Parametric Excitation of a Bose-Einstein Condensate: From Faraday Waves to Granulation 

      Nguyen, J.H.V.; Tsatsos, M.C.; Luo, D.; Lode, A.U.J.; Telles, G.D.; (2019)
      We explore, both experimentally and theoretically, the response of an elongated Bose-Einstein condensate to modulated interactions. We identify two distinct regimes differing in modulation frequency and modulation strength. Longitudinal surface waves are generated either resonantly or parametrically for modulation frequencies near the radial trap ...
    • Parsimonious Inference of Hybridization in the Presence of Incomplete Lineage Sorting 

      (2013)
      Hybridization plays an important evolutionary role in several groups of organisms. A phylogenetic approach to detect hybridization entails sequencing multiple loci across the genomes of a group of species of interest, reconstructing their gene trees, and taking their differences as indicators of hybridization. However, methods that follow this approach ...
    • Partial melting of a depleted peridotite metasomatized by a MORB-derived hydrous silicate melt – Implications for subduction zone magmatism 

      Lara, Michael; Dasgupta, Rajdeep (2020)
      Recent geodynamic models and geothermometers suggest that slabs in intermediate to hot subduction zone cross the water-saturated basalt solidus, indicating that hydrous silicate melts are important agents of mass transfer from slab to mantle wedge beneath arcs. Yet the effects of basaltic crust-derived hydrous melt fluxing on mantle wedge melting are ...