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    Snapshot spectrally encoded fluorescence imaging through a fiber bundle

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    Author
    Bedard, Noah
    Tkaczyk, Tomasz S.
    Date
    2012
    Citation
    Bedard, Noah and Tkaczyk, Tomasz S.. "Snapshot spectrally encoded fluorescence imaging through a fiber bundle." Journal of Biomedical Optics, 17, no. 8 (2012) 80508. http://dx.doi.org/10.1117/1.JBO.17.8.080508.
    Published Version
    http://dx.doi.org/10.1117/1.JBO.17.8.080508
    Abstract
    Fiber optic endomicroscopy is a valuable tool for clinical diagnostics and animal studies because it can capture images of tissue in vivo with subcellular resolution. Current configurations for endomicroscopes have either limited spatial resolution or require a scanning mechanism at the distal end of the fiber, which can slow imaging speed and increase the probe size. We present a novel configuration that provides high contrast 350 × 350 pixel images at 7.2 frames per second, without the need for mechanical scanning at the proximal or distal end of the fiber. The proofof- concept benchtop system is tested in fluorescence mode and can resolve 1.5 μm features of a high resolution 1951 USAF target.
    Keyword
    endomicroscope; spectral encoding; imaging
    Type
    Journal article
    Citable link to this page
    http://hdl.handle.net/1911/71770
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    • Bioengineering Publications [397]
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    Managed by the Digital Scholarship Services at Fondren Library, Rice University
    Physical Address: 6100 Main Street, Houston, Texas 77005
    Mailing Address: MS-44, P.O.BOX 1892, Houston, Texas 77251-1892