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dc.contributor.authorBedard, Noah
Schwarz, Richard A.
Hu, Aaron
Bhattar, Vijayashree
Howe, Jana
Williams, Michelle D.
Gillenwater, Ann M.
Richards-Kortum, Rebecca
Tkaczyk, Tomasz S.
dc.date.accessioned 2013-06-28T17:49:00Z
dc.date.available 2013-06-28T17:49:00Z
dc.date.issued 2013
dc.identifier.citation Bedard, Noah, Schwarz, Richard A., Hu, Aaron, et al.. "Multimodal snapshot spectral imaging for oral cancer diagnostics: a pilot study." Biomedical Optics Express, 4, no. 6 (2013) Optical Society of America: 938-949. http://dx.doi.org/10.1364/BOE.4.000938.
dc.identifier.urihttps://hdl.handle.net/1911/71484
dc.description.abstract Optical imaging and spectroscopy have emerged as effective tools for detecting malignant changes associated with oral cancer. While clinical studies have demonstrated high sensitivity and specificity for detection, current devices either interrogate a small region or can have reduced performance for some benign lesions. We describe a snapshot imaging spectrometer that combines the large field-of-view of widefield imaging with the diagnostic strength of spectroscopy. The portable device can stream RGB images at 7.2 frames per second and record both autofluorescence and reflectance spectral datacubes in < 1 second. We report initial data from normal volunteers and oral cancer patients.
dc.language.iso eng
dc.publisher Optical Society of America
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.title Multimodal snapshot spectral imaging for oral cancer diagnostics: a pilot study
dc.type Journal article
dc.contributor.funder National Institutes of Health
dc.citation.journalTitle Biomedical Optics Express
dc.citation.volumeNumber 4
dc.citation.issueNumber 6
dc.embargo.terms none
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1364/BOE.4.000938
dc.identifier.pmcid PMC3675872
dc.identifier.pmid 23760882
dc.identifier.grantID R01CA124319 (National Institutes of Health)
dc.identifier.grantID R21EB009186 (National Institutes of Health)
dc.type.publication publisher version
dc.citation.firstpage 938
dc.citation.lastpage 949


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