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dc.contributor.authorGao, Simon S.
Raphael, Patrick D.
Wang, Rosalie
Park, Jesung
Xia, Anping
Applegate, Brian E.
Oghalai, John S.
dc.date.accessioned 2013-04-29T18:56:22Z
dc.date.available 2013-04-29T18:56:22Z
dc.date.issued 2013
dc.identifier.citation Gao, Simon S., Raphael, Patrick D., Wang, Rosalie, et al., . "In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography." Journal of Biomedical Optics Express, 4, no. 2 (2013) http://dx.doi.org/10.1364/BOE.4.000230.
dc.identifier.urihttp://hdl.handle.net/1911/71011
dc.description.abstract Sound transduction within the auditory portion of the inner ear, the cochlea, is a complex nonlinear process. The study of cochlear mechanics in large rodents has provided important insights into cochlear function. However, technological and experimental limitations have restricted studies in mice due to their smaller cochlea. These challenges are important to overcome because of the wide variety of transgenic mouse strains with hearing loss mutations that are available for study. To accomplish this goal, we used spectral domain optical coherence tomography to visualize and measure sound-induced vibrations of intracochlear tissues. We present, to our knowledge, the first vibration measurements from the apex of an unopened mouse cochlea.
dc.language.iso eng
dc.title In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography
dc.type Journal article
dc.contributor.funder U.S. Department of Defense
dc.citation.journalTitle Journal of Biomedical Optics Express
dc.citation.volumeNumber 4
dc.citation.issueNumber 2
dc.contributor.publisher Optical Society of America
dc.embargo.terms none
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1364/BOE.4.000230
dc.identifier.pmcid PMC3567710
dc.identifier.pmid 23411442
dc.identifier.grantID W81XWH-11-2-0004 (U.S. Department of Defense)
dc.type.publication publisher version


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