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dc.contributor.authorSaakian, David B.
Deem, Michael W.
Hu, Chin-Kun
dc.date.accessioned 2013-03-13T19:59:09Z
dc.date.available 2014-03-19T05:10:03Z
dc.date.issued 2012-04
dc.identifier.citation Saakian, David B., Deem, Michael W. and Hu, Chin-Kun. "Finite population size effects in quasispecies models with single-peak fitness landscape." EPL, 98, (2012) IOP Publishing: 18001. http://dx.doi.org/10.1209/0295-5075/98/18001.
dc.identifier.urihttps://hdl.handle.net/1911/70576
dc.description.abstract We consider finite population size effects for Crow-Kimura and Eigen quasispecies models with single-peak fitness landscape. We formulate accurately the iteration procedure for the finite population models, then derive the Hamilton-Jacobi equation (HJE) to describe the dynamic of the probability distribution. The steady-state solution of HJE gives the variance of the mean fitness. Our results are useful for understanding the population sizes of viruses in which the infinite population models can give reliable results for biological evolution problems.
dc.language.iso eng
dc.publisher IOP Publishing
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.title Finite population size effects in quasispecies models with single-peak fitness landscape
dc.type Journal article
dc.citation.journalTitle EPL
dc.citation.volumeNumber 98
dc.embargo.terms 1 year
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1209/0295-5075/98/18001
dc.type.publication publisher version
dc.citation.firstpage 18001


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