Now showing items 68-79 of 79

    • TFEB regulates lysosomal proteostasis 

      Song, Wensi; Wang, Fan; Savini, Marzia; Ake, Ashley; di Ronza, Alberto; Sardiello, Marco; Segatori, Laura (2013)
      Loss-of-function diseases are often caused by destabilizing mutations that lead to protein misfolding and degradation. Modulating the innate protein homeostasis (proteostasis) capacity may lead to rescue of native folding ...
    • Theoretical analysis of selectivity mechanisms in molecular transport through channels and nanopores 

      Agah, Shaghayegh; Pasquali, Matteo; Kolomeisky, Anatoly B. (2015)
      Selectivity is one of the most fundamental concepts in natural sciences, and it is also critically important in various technological, industrial, and medical applications. Although there are many experimental methods that ...
    • Thermodynamic perturbation theory for associating fluids with small bond angles: Effects of steric hindrance, ring formation, and double bonding 

      Marshall, Bennett D.; Chapman, Walter G. (2013)
      We develop a comprehensive approach to model associating fluids with small bond angles using Wertheim's perturbation theory. We show theoretically and through Monte Carlo simulations that as bond angle is varied various ...
    • Thermoresponsive PNIPAAM bottlebrush polymers with tailored side-chain length and end-group structure 

      Li, Xianyu; ShamsiJazeyi, Hadi; Pesek, Stacy L.; Agrawal, Aditya; Hammouda, Boualem; Verduzco, Rafael (2014)
      We explore the phase behaviour, solution conformation, and interfacial properties of bottlebrush polymers with side-chains comprised of poly(N-isopropylacrylamide) (PNIPAAM), a thermally responsive polymer that exhibits a ...
    • Three new branched chain equations of state based on Wertheim's perturbation theory 

      Marshall, Bennett D.; Chapman, Walter G. (2013)
      In this work, we present three new branched chain equations of state (EOS) based on Wertheimメs perturbation theory. The first represents a slightly approximate general branched chain solution of Wertheimメs second order ...
    • Tissue engineering perfusable cancer models 

      Fong, E.L.; Santoro, M.; Farach-Carson, M.C.; Kasper, F.K.; Mikos, A.G. (2014)
      The effect of fluid flow on cancer progression is currently not well understood, highlighting the need for perfused tumor models to close this gap in knowledge. Enabling biological processes at the cellular level to be ...
    • Transport mechanism in granular Ni deposited on carbon nanotubes fibers 

      Salvato, M.; Lucci, M.; Ottaviani, I.; Cirillo, M.; Tamburri, E.; Orlanducci, S.; Terranova, M.L.; Notarianni, M.; Young, C.C.; Behabtu, N.; Pasquali, M. (2012)
      We investigate the transport properties of granular nickel electrodeposited on carbon nanotube fibers by measuring the electrical resistance and the current voltage characteristics as a function of the temperature. The ...
    • Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism 

      Zhao, Hongyun; Yang, Lifeng; Baddour, Joelle; Achreja, Abhinav; Bernard, Vincent; Moss, Tyler; Marini, Juan C.; Tudawe, Thavisha; Seviour, Elena G.; San Lucas, F. Anthony; Alvarez, Hector; Gupta, Sonal; Maiti, Sourindra N.; Cooper, Laurence; Peehl, Donna; Ram, Prahlad T.; Maitra, Anirban; Nagrath, Deepak (2016)
      Cancer-associated fibroblasts (CAFs) are a major cellular component of tumor microenvironment in most solid cancers. Altered cellular metabolism is a hallmark of cancer, and much of the published literature has focused on ...
    • Unimolecular Submersible Nanomachines. Synthesis, Actuation, and Monitoring 

      García-López, Víctor; Chiang, Pinn-Tsong; Chen, Fang; Ruan, Gedeng; Martí, Angel A.; Kolomeisky, Anatoly B.; Wang, Gufeng; Tour, James M. (2015)
      Unimolecular submersible nanomachines (USNs) bearing light-driven motors and fluorophores are synthesized. NMR experiments demonstrate that the rotation of the motor is not quenched by the fluorophore and that the motor ...
    • Using Nonionic Surfactants for Production of Semiconductor-type Carbon Nanotubes by Gel-based Affinity Chromatography 

      Gangoli, Varun Shenoy; Azhang, Juyan; Willett, Taryn T.; Gelwick, Sean A.; Haroz, Erik H.; Kono, Junichiro; Hauge, Robert H.; Wong, Michael S. (2014)
      Single-wall carbon nanotubes (SWCNTs) have remarkable properties based on their electronic properties, i.e., metallic or semiconducting types, but as-grown SWCNTs contain a mixture of both types. Presented here is an ...
    • Visualizing oil displacement with foam in a microfluidic device with permeability contrast 

      Conn, Charles A.; Ma, Kun; Hirasaki, George J.; Biswal, Sibani Lisa (2014)
      Foam mobility control and novel oil displacement mechanisms were observed in a microfluidic device representing a porous media system with layered permeability. Foam was pre-generated using a flow focusing microfluidic ...
    • Volcano-shape glycerol oxidation activity of palladium-decorated gold nanoparticles 

      Zhao, Zhun; Arentz, Joni; Pretzer, Lori A.; Limpornpipat, Pongsak; Clomburg, James M.; Gonzalez, Ramon; Schweitzer, Neil M.; Wu, Tianpin; Miller, Jeffrey T.; Wong, Michael S. (2014)
      Bimetallic PdAu catalysts are more active than monometallic ones for the selective oxidation of alcohols, but the reasons for improvement remain insufficiently detailed. A metal-on-metal material can probe the structure–catalysis ...