Now showing items 55-74 of 79

    • A Rapid and Sensitive Method for Measuring NAcetylglucosaminidase Activity in Cultured Cells 

      Mauri, Victor; Lotfi, Parisa; Segatori, Laura; Sardiello, Marco (2013)
      A rapid and sensitive method to quantitatively assess N-acetylglucosaminidase (NAG) activity in cultured cells is highly desirable for both basic research and clinical studies. NAG activity is deficient in cells from ...
    • Remodeling the Proteostasis Network to Rescue Glucocerebrosidase Variants by Inhibiting ER-Associated Degradation and Enhancing ER Folding 

      Wang, Fan; Segatori, Laura (2013)
      Gaucherメs disease (GD) is characterized by loss of lysosomal glucocerebrosidase (GC) activity. Mutations in the gene encoding GC destabilize the proteinメs native folding leading to ER-associated degradation (ERAD) of the ...
    • Ring-locking enables selective anhydrosugar synthesis from carbohydrate pyrolysis 

      Chen, Li; Zhao, Jinmo; Pradhan, Sivaram; Brinson, Bruce E.; Scuseria, Gustavo E.; Zhang, Z. Conrad; Wong, Michael S. (2016)
      The selective production of platform chemicals from thermal conversion of biomass-derived carbohydrates is challenging. As precursors to natural products and drug molecules, anhydrosugars are difficult to synthesize from ...
    • Role of Gas Type on Foam Transport in Porous Media 

      Zeng, Yongchao; Farajzadeh, Rouhi; Eftekhari, Ali Akbar; Vincent-Bonnieu, Sebastien; Muthuswamy, Aarthi; Rossen, William R.; Hirasaki, George J.; Biswal, Sibani L. (2016)
      We present the results of an experimental investigation of the effect of gas type and composition on foam transport in porous media. Steady-state foam strengths with respect to three cases of distinct gases and two cases ...
    • Role of Gas Type on Foam Transport in Porous Media 

      Zeng, Yongchao; Farajzadeh, Rouhi; Eftekhari, Ali Akbar; Vincent-Bonnieu, Sebastien; Muthuswamy, Aarthi; Rossen, William R.; Hirasaki, George J.; Biswal, Sibani L. (2016)
      We present the results of an experimental investigation of the effect of gas type and composition on foam transport in porous media. Steady-state foam strengths with respect to three cases of distinct gases and two cases ...
    • Strategies for controlled delivery of biologics for cartilage repair 

      Lam, Johnny; Lu, Steven; Kasper, F. Kurtis; Mikos, Antonios G. (2015)
      The delivery of biologics is an important component in the treatment of osteoarthritis and the functional restoration of articular cartilage. Numerous factors have been implicated in the cartilage repair process, but the ...
    • Strong, Light, Multifunctional Fibers of Carbon Nanotubes with Ultrahigh Conductivity 

      Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Kleinerman, Olga; Wang, Xuan; Ma, Anson W.K.; Bengio, E. Amram; ter Waarbeek, Ron F.; de Jong, Jorrit J.; Hoogerwerf, Ron E.; Fairchild, Steven B.; Ferguson, John B.; Maruyama, Benji; Kono, Junichiro; Talmon, Yeshayahu; Cohen, Yachin; Otto, Marcin J.; Pasquali, Matteo (2013)
      Broader applications of carbon nanotubes to real-world problems have largely gone unfulfilled because of difficult material synthesis and laborious processing. We report high-performance multifunctional carbon nanotube ...
    • Structure, function, self-assembly, and applications of bottlebrush copolymers 

      Verduzco, Rafael; Li, Xianyu; Pesek, Stacy L.; Stein, Gila E. (2015)
      Bottlebrush polymers are a type of branched or graft polymer with polymeric side-chains attached to a linear backbone, and the unusual architectures of bottlebrushes provide a number of unique and potentially useful ...
    • Supramolecular block copolymer photovoltaics through ureido-pyrimidinone hydrogen bonding interactions 

      Lin, Yen-Hao; Nie, Wanyi; Tsai, Hsinhan; Li, Xiaoyi; Gupta, Gautam; Mohite, Aditya D.; Verduzco, Rafael (2016)
      A challenge in the development of bulk heterojunction organic photovoltaics (BHJ OPVs) is achieving a desirable nanoscale morphology. This is particularly true for polymer blend OPVs in which large-scale phase separation ...
    • Switchable Diamine Surfactants for CO2 Mobility Control in Enhanced Oil Recovery and Sequestration 

      Elhag, Amro S.; Chen, Yunshen; Reddy, Prathima P.; Noguera, Jose A.; Ou, Anne Marie; Hirasaki, George J.; Nguyen, Quoc P.; Biswal, Sibani L.; Johnston, Keith P. (2014)
      The design of switchable amine surfactants for CO2 EOR in carbonate reservoirs at high temperatures is challenging because of the increase in the pH due to dissolution of calcium carbonate at acidic conditions. The increased ...
    • Synergistic Gold-Bismuth Catalysis for Non-Mercury Hydrochlorination of Acetylene to Vinyl Chloride Monomer 

      Zhou, Kai; Wang, Wei; Zhao, Zhun; Luo, Guohua; Miller, Jeffrey T.; Wong, Michael S.; Wei, Fei (2014)
      Gold has been proposed as an environmentally friendly catalyst for acetylene hydrochlorination for vinyl chloride monomer synthesis by replacing the commercially used mercury catalyst. However, long life with excellent ...
    • Synthesis and Crystal Structure of Gold Nanobelts 

      Payne, Courtney M.; Tsentalovich, Dmitri E.; Benoit, Denise N.; Anderson, Lindsey J.E.; Guo, Wenhua; Colvin, Vicki L.; Pasquali, Matteo; Hafner, Jason H. (2014)
      Gold nanobelts were synthesized by the reduction of tetrachloroauric acid with ascorbic acid in the presence of the surfactants cetyltrimethylammonium bromide and sodium dodecylsulfate. The resulting structures have ...
    • Synthesis of oligo(poly(ethylene glycol) fumarate) 

      Kinard, Lucas A.; Kasper, F. Kurtis; Mikos, Antonios G. (2012)
      This protocol describes the synthesis of oligo(poly(ethylene glycol) fumarate) (OPF) (1-35 kDa)(a polymer useful for tissue engineering applications) by a one-pot reaction of poly(ethylene glycol) (PEG) and fumaryl chloride. ...
    • TFEB regulates lysosomal proteostasis 

      Song, Wensi; Wang, Fan; Savini, Marzia; Ake, Ashley; di Ronza, Alberto; Sardiello, Marco; Segatori, Laura (2013)
      Loss-of-function diseases are often caused by destabilizing mutations that lead to protein misfolding and degradation. Modulating the innate protein homeostasis (proteostasis) capacity may lead to rescue of native folding ...
    • Theoretical analysis of selectivity mechanisms in molecular transport through channels and nanopores 

      Agah, Shaghayegh; Pasquali, Matteo; Kolomeisky, Anatoly B. (2015)
      Selectivity is one of the most fundamental concepts in natural sciences, and it is also critically important in various technological, industrial, and medical applications. Although there are many experimental methods that ...
    • Thermodynamic perturbation theory for associating fluids with small bond angles: Effects of steric hindrance, ring formation, and double bonding 

      Marshall, Bennett D.; Chapman, Walter G. (2013)
      We develop a comprehensive approach to model associating fluids with small bond angles using Wertheim's perturbation theory. We show theoretically and through Monte Carlo simulations that as bond angle is varied various ...
    • Thermoresponsive PNIPAAM bottlebrush polymers with tailored side-chain length and end-group structure 

      Li, Xianyu; ShamsiJazeyi, Hadi; Pesek, Stacy L.; Agrawal, Aditya; Hammouda, Boualem; Verduzco, Rafael (2014)
      We explore the phase behaviour, solution conformation, and interfacial properties of bottlebrush polymers with side-chains comprised of poly(N-isopropylacrylamide) (PNIPAAM), a thermally responsive polymer that exhibits a ...
    • Three new branched chain equations of state based on Wertheim's perturbation theory 

      Marshall, Bennett D.; Chapman, Walter G. (2013)
      In this work, we present three new branched chain equations of state (EOS) based on Wertheimメs perturbation theory. The first represents a slightly approximate general branched chain solution of Wertheimメs second order ...
    • Tissue engineering perfusable cancer models 

      Fong, E.L.; Santoro, M.; Farach-Carson, M.C.; Kasper, F.K.; Mikos, A.G. (2014)
      The effect of fluid flow on cancer progression is currently not well understood, highlighting the need for perfused tumor models to close this gap in knowledge. Enabling biological processes at the cellular level to be ...
    • Transport mechanism in granular Ni deposited on carbon nanotubes fibers 

      Salvato, M.; Lucci, M.; Ottaviani, I.; Cirillo, M.; Tamburri, E.; Orlanducci, S.; Terranova, M.L.; Notarianni, M.; Young, C.C.; Behabtu, N.; Pasquali, M. (2012)
      We investigate the transport properties of granular nickel electrodeposited on carbon nanotube fibers by measuring the electrical resistance and the current voltage characteristics as a function of the temperature. The ...