Now showing items 41-60 of 168

    • Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli 

      Mazumdar, Suman; Blankschien, Matthew D; Clomburg, James M; Gonzalez, Ramon (2013)
      Due to its abundance and low-price, glycerol has become an attractive carbon source for the industrial production of value-added fuels and chemicals. This work reports the engineering of E. coli for the efficient conversion ...
    • Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures 

      Vergara, Mauricio; Berrios, Julio; Martínez, Irene; Díaz-Barrera, Alvaro; Acevedo, Cristian; Reyes, Juan G.; Gonzalez, Ramon; Altamirano, Claudia (2015)
      Background: Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human therapeutic applications mainly because of their capability to perform proper folding and glycosylation processes. ...
    • Entropic and Enthalpic Effects in Thin Film Blends of Homopolymers and Bottlebrush Polymers 

      Mah, Adeline Huizhen; Laws, Travis; Li, Wei; Mei, Hao; Brown, Chance C.; Ievlev, Anton; Kumar, Rajeev; Verduzco, Rafael; Stein, Gila E. (2019)
      We present a combined experimental and computational study of surface segregation in thin films of nearly athermal blends of linear and bottlebrush polymers. The lengths of bottlebrush backbone (Nb), bottlebrush side chain ...
    • Evaluating the Transport Behavior of CO2ᅠFoam in the Presence of Crude Oil under High-Temperature and High-Salinity Conditions for Carbonate Reservoirs 

      Jian, Guoqing; Zhang, Leilei; Da, Chang; Puerto, Maura; Johnston, Keith P.; Biswal, Sibani L.; Hirasaki, George J. (2019)
      An amine-based surfactant, Duomeen TTM, was evaluated for foam flooding in carbonate rock at high temperature (120 °C), high salinity (22% total dissolved solids), and CO2–oil miscible conditions. We demonstrate enhanced ...
    • Evolutionary Relationships Between Low Potential Ferredoxin and Flavodoxin Electron Carriers 

      Campbell, Ian J.; Bennett, George N.; Silberg, Jonathan J. (2019)
      Proteins from the ferredoxin (Fd) and flavodoxin (Fld) families function as low potential electrical transfer hubs in cells, at times mediating electron transfer between overlapping sets of oxidoreductases. To better ...
    • Examining Asphaltene Solubility on Deposition in Model Porous Media 

      Lin, Yu-Jiun; He, Peng; Tavakkoli, Mohammad; Mathew, Nevin Thunduvila; Fatt, Yap Yit; Chai, John C.; Goharzadeh, Afshin; Vargas, Francisco M.; Biswal, Sibani Lisa (2016)
      Asphaltenes are known to cause severe flow assurance problems in the near-wellbore region of oil reservoirs. Understanding the mechanism of asphaltene deposition in porous media is of great significance for the development ...
    • Experimental realization of crossover in shape and director field of nematic tactoids 

      Jamali, Vida; Behabtu, Natnael; Senyuk, Bohdan; Lee, J. Alex; Smalyukh, Ivan I.; van der Schoot, Paul; Pasquali, Matteo (2015)
      Spindle-shaped nematic droplets (tactoids) form in solutions of rod-like molecules at the onset of the liquid crystalline phase. Their unique shape and internal structure result from the interplay of the elastic deformation ...
    • Fabrication and characterization of multiscale electrospun scaffolds for cartilage regeneration 

      Levorson, Erica J.; Sreerekha, Perumcherry Raman; Chennazhi, Krishna Prasad; Kasper, F. Kurtis; Nair, Shantikumar V.; Mikos, Antonios G. (2013)
      Recently, scaffolds for tissue regeneration purposes have been observed to utilize nanoscale features in an effort to reap the cellular benefits of scaffold features resembling extracellular matrix (ECM) components. However, ...
    • Facile Graphene Oxide Preparation by Microwave-Assisted Acid Method 

      Viana, Marcelo M.; Lima, Meiriane C.F.S.; Forsythe, Jerimiah C.; Gangoli, Varun S.; Cho, Minjung; Cheng, Yinhong; Silva, Glaura G.; Wong, Michael S.; Caliman, Vinicius (2015)
      Few-layered graphene oxide (GO) was prepared using a fast and energy-saving method by microwave-assisted acid technique. The oxygenated groups existing on the GO surface were determined using UV-Vis, X-ray photoelectron ...
    • Facilitation of DNA loop formation by protein–DNA non-specific interactions 

      Shin, Jaeoh; Kolomeisky, Anatoly B. (2019)
      Complex DNA topological structures, including polymer loops, are frequently observed in biological processes when protein molecules simultaneously bind to several distant sites on DNA. However, the molecular mechanisms of ...
    • From strings to coils: Rotational dynamics of DNA-linked colloidal chains 

      Kuei, Steve; Garza, Burke; Biswal, Sibani Lisa (2017)
      We investigate the dynamical behavior of deformable filaments experimentally using a tunable model system consisting of linked paramagnetic colloidal particles, where the persistence length lp, the contour length lc, and ...
    • Gelatin carriers for drug and cell delivery in tissue engineering 

      Santoro, Marco; Tatara, Alexander M.; Mikos, Antonios G. (2014)
      The ability of gelatin to form complexes with different drugs has been investigated for controlled release applications. Gelatin parameters, such as crosslinking density and isoelectric point, have been tuned in order to ...
    • Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein 

      Kilpatrick, Kiri; Zeng, Yimeng; Hancock, Tommy; Segatori, Laura (2015)
      Aggregation of α-synuclein (α-syn) is associated with the development of a number of neurodegenerative diseases, including Parkinson’s disease (PD). The formation of α-syn aggregates results from aberrant accumulation of ...
    • High efficiency carbon nanotube thread antennas 

      Bengio, E. Amram; Senic, Damir; Taylor, Lauren W.; Tsentalovich, Dmitri E.; Chen, Peiyu; Holloway, Christopher L.; Babakhani, Aydin; Long, Christian J.; Novotny, David R.; Booth, James C.; Orloff, Nathan D.; Pasquali, Matteo (2017)
      Although previous research has explored the underlying theory of high-frequency behavior of carbon nanotubes (CNTs) and CNT bundles for antennas, there is a gap in the literature for direct experimental measurements of ...
    • High pressure measurements and molecular modeling of the water content of acid gas containing mixtures 

      Fouad, Wael A.; Yarrison, Matt; Song, Kyoo Y.; Cox, Kenneth R.; Chapman, Walter G. (2015)
      Water content of three carbon dioxide containing natural gas mixtures in equilibrium with an aqueous phase was measured using a dynamic saturation method. Measurements were performed up to high temperatures (477.6 K = 400°F) ...
    • High-Ampacity Power Cables of Tightly-Packed and Aligned Carbon Nanotubes 

      Wang, Xuan; Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Pasquali, Matteo; Kono, Junichiro (2014)
      The current-carrying capacity (CCC), or ampacity, of highly-conductive, light, and strong carbon nanotube (CNT) fibers is characterized by measuring their failure current density (FCD) and continuous current rating (CCR) ...
    • Highly Defective UiO-66 Materials for the Adsorptive Removal of Perfluorooctanesulfonate 

      Clark, Chelsea A.; Heck, Kimberly N.; Powell, Camilah D.; Wong, Michael S. (2019)
      Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant that is bioaccumulative and toxic. While its use in most countries has been restricted to certain industrial applications due to environmental and health ...
    • Highly Flexible Self-Assembled V2O5 Cathodes Enabled by Conducting Diblock Copolymers 

      An, Hyosung; Mike, Jared; Smith, Kendall A.; Swank, Lisa; Lin, Yen-Hao; Pesek, Stacy L.; Verduzco, Rafael; Lutkenhaus, Jodie L. (2015)
      Mechanically robust battery electrodes are desired for applications in wearable devices, flexible displays, and structural energy and power. In this regard, the challenge is to balance mechanical and electrochemical ...
    • HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer 

      Mondal, Susmita; Roy, Debarshi; Camacho-Pereira, Juliana; Khurana, Ashwani; Chini, Eduardo; Yang, Lifeng; Baddour, Joelle; Stilles, Katherine; Padmabandu, Seth; Leung, Sam; Kalloger, Steve; Gilks, Blake; Lowe, Val; Dierks, Thomas; Hammond, Edward; Dredge, Keith; Nagrath, Deepak; Shridhar, Viji (2015)
      Warburg effect has emerged as a potential hallmark of many cancers. However, the molecular mechanisms that led to this metabolic state of aerobic glycolysis, particularly in ovarian cancer (OVCA) have not been completely ...
    • Human Omental-Derived Adipose Stem Cells Increase Ovarian Cancer Proliferation, Migration, and Chemoresistance 

      Nowicka, Aleksandra; Marini, Frank C.; Solley, Travis N.; Elizondo, Paula B.; Zhang, Yan; Sharp, Hadley J.; Broaddus, Russell; Kolonin, Mikhail; Mok, Samuel C.; Thompson, Melissa S.; Woodward, Wendy A.; Lu, Karen; Salimian, Bahar; Nagrath, Deepak; Klopp, Ann H. (2013)
      Objectives: Adipose tissue contains a population of multipotent adipose stem cells (ASCs) that form tumor stroma and can promote tumor progression. Given the high rate of ovarian cancer metastasis to the omental adipose, ...