Now showing items 150-169 of 403

    • Grb2 monomer–dimer equilibrium determines normal versus oncogenic function 

      Ahmed, Zamal; Timsah, Zahra; Suen, Kin M.; Cook, Nathan P.; Lee, Gilbert R. IV; Lin, Chi-Chuan; Gagea, Mihai; Marti, Angel A.; Ladbury, John E. (2015)
      The adaptor protein growth factor receptor-bound protein 2 (Grb2) is ubiquitously expressed in eukaryotic cells and involved in a multitude of intracellular protein interactions. Grb2 plays a pivotal role in tyrosine ...
    • Hierarchically Structured Magnetic Nanoconstructs with Enhanced Relaxivity and Cooperative Tumor Accumulation 

      Gizzatov, Ayrat; Key, Jaehong; Aryal, Santosh; Ananta, Jeyarama; Cervadoro, Antonio; Palange, Anna Lisa; Fasano, Matteo; Stigliano, Cinzia; Zhong, Meng; Di Mascolo, Daniele; Guven, Adem; Chiavazzo, Eliodoro; Asinari, Pietro; Liu, Xuewu; Ferrari, Mauro; Wilson, Lon J.; Decuzzi, Paolo (2014)
      Iron oxide nanoparticles are formidable multifunctional systems capable of contrast enhancement in magnetic resonance imaging, guidance under remote fields, heat generation, and biodegradation. Yet, this potential is ...
    • High Chromaticity Aluminum Plasmonic Pixels for Active Liquid Crystal Displays 

      Olson, Jana; Manjavacas, Alejandro; Basu, Tiyash; Huang, Da; Schlather, Andrea E.; Zheng, Bob; Halas, Naomi; Nordlander, Peter; Link, Stephan (2016)
      Chromatic devices such as flat panel displays could, in principle, be substantially improved by incorporating aluminum plasmonic nanostructures instead of conventional chromophores that are susceptible to photobleaching. ...
    • High ionic strength narrows the population of sites participating in protein ion-exchange adsorption: A single-molecule study 

      Kisley, Lydia; Chen, Jixin; Mansur, Andrea P.; Dominguez-Medina, Sergio; Kulla, Eliona; Kang, Marci; Shuang, Bo; Kourentzi, Katerina; Poongavanam, Mohan-Vivekanandan; Dhamane, Sagar; Willson, Richard C.; Landes, Christy F. (2014)
      The retention and elution of proteins in ion-exchange chromatography is routinely controlled by adjusting the mobile phase salt concentration. It has repeatedly been observed, as judged from adsorption isotherms, that the ...
    • High Performance Electrocatalytic Reaction of Hydrogen and Oxygen on Ruthenium Nanoclusters 

      Ye, Ruquan; Liu, Yuanyue; Peng, Zhiwei; Wang, Tuo; Jalilov, Almaz S.; Yakobson, Boris I.; Wei, Su-Huai; Tour, James M. (2017)
      The development of catalytic materials for the hydrogen oxidation, hydrogen evolution, oxygen reduction or oxygen evolution reactions with high reaction rates and low overpotentials are key goals for the development of ...
    • High Precision Fractionator for use with Density Gradient Ultracentrifugation 

      Kadria-Vili, Yara; Canning, Griffin; Bachilo, Sergei M.; Weisman, R. Bruce (2014)
      The recent application of density gradient ultracentrifugation (DGU) for structural sorting of single-walled carbon nanotube samples has created a need for highly selective extraction of closely spaced layers formed in the ...
    • High-Ampacity Power Cables of Tightly-Packed and Aligned Carbon Nanotubes 

      Wang, Xuan; Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Pasquali, Matteo; Kono, Junichiro (2014)
      The current-carrying capacity (CCC), or ampacity, of highly-conductive, light, and strong carbon nanotube (CNT) fibers is characterized by measuring their failure current density (FCD) and continuous current rating (CCR) ...
    • High-Performance Hybrid Bismuth–Carbon Nanotube Based Contrast Agent for X-ray CT Imaging 

      Hernández-Rivera, Mayra; Kumar, Ish; Cho, Stephen Y.; Cheong, Benjamin Y.; Pulikkathara, Merlyn X.; Moghaddam, Sakineh E.; Whitmire, Kenton H.; Wilson, Lon J. (2017)
      Carbon nanotubes (CNTs) have been used for a plethora of biomedical applications, including their use as delivery vehicles for drugs, imaging agents, proteins, DNA, and other materials. Here, we describe the synthesis and ...
    • High-Performance Hydrogen Evolution from MoS2(1–x)P x Solid Solution 

      Ye, Ruquan; Vicente, Paz Del Angel; Liu, Yuanyue; Arellano-Jimenez, Josefina; Peng, Zhiwei; Wang, Tuo; Li, Yilun; Yakobson, Boris I.; Wei, Su-Huai; Yacaman, Miguel Jose; Tour, James M. (2016)
      A MoS2(1-x)Px solid solution (x = 0 to 1) is formed by thermally annealing mixtures of MoS2 and red phosphorus. The effective and stable electrocatalyst for hydrogen evolution in acidic solution holds promise for replacing ...
    • High-yield single-step catalytic growth of graphene nanostripes by plasma enhanced chemical vapor deposition 

      Hsu, Chen-Chih; Bagley, Jacob D.; Teague, Marcus L.; Tseng, Wei-Shiuan; Yang, Kathleen L.; Zhang, Yiran; Li, Yiliang; Li, Yilun; Tour, James M.; Yeh, N.-C. (2018)
      We report a single-step growth process of graphene nanostripes (GNSPs) by adding certain substituted aromatics (e.g., 1,2-dichlorobenzene) as precursors during the plasma enhanced chemical vapor deposition (PECVD). Without ...
    • Highly Angiogenic Peptide Nanofibers 

      Kumar, Vivek A.; Taylor, Nichole L.; Shi, Siyu; Wang, Benjamin K.; Jalan, Abhishek A.; Kang, Marci K.; Wickremasinghe, Navindee C.; Hartgerink, Jeffrey D. (2015)
      Major limitations of current tissue regeneration approaches using artificial scaffolds are fibrous encapsulation, lack of host cellular infiltration, unwanted immune responses, surface degradation preceding biointegration, ...
    • Hot embossed polyethylene through-hole chips for bead-based microfluidicdevices 

      Chou, Jie; Du, Nan; Ou, Tina; Floriano, Pierre N.; Christodoulides, Nicolaos; McDevitt, John T. (2013)
      Over the past decade, there has been a growth of interest in the translation of microfluidic systems into real-world clinical practice, especially for use in point-of-care or near patient settings. While initial fabrication ...
    • How the interplay between mechanical and non-mechanical interactions affects multiple kinesin dynamics 

      Uppulury, Karthik; Efremov, Artem K.; Driver, Jonathan W.; Jamison, D. Kenneth; Diehl, Michael R.; Kolomeisky, Anatoly B. (2012)
      Intracellular transport is supported by enzymes called motor proteins that are often coupled to the same cargo and function collectively. Recent experiments and theoretical advances have been able to explain certain behaviors ...
    • How to accelerate protein search on DNA: Location and dissociation 

      Kolomeisky, Anatoly B.; Veksler, Alex (2012)
      One of the most important features of biological systems that controls their functioning is the ability of protein molecules to find and recognize quickly specific target sites on DNA. Although these phenomena have been ...
    • Hybrid organic-inorganic inhibitors of a PDZ-peptide interaction that regulates CFTR endocytic fate 

      Kundu, Rituparna; Cushing, Patrick R.; Popp, Brian V.; Zhao, Yu; Madden, Dean R.; Ball, Zachary T. (2012)
    • Hydrogen Diffusion and Stabilization in Single-Crystal VO2 Micro/Nanobeams by Direct Atomic Hydrogenation 

      Lin, Jian; Ji, Heng; Swift, Michael W.; Hardy, Will J.; Peng, Zhiwei; Fan, Xiujun; Nevidomskyy, Andriy H.; Tour, James M.; Natelson, Douglas (2014)
      We report measurements of the diffusion of atomic hydrogen in single crystalline VO2 micro/nanobeams by direct exposure to atomic hydrogen, without catalyst. The atomic hydrogen is generated by a hot filament, and the ...
    • Hydrolysis of Guanosine Triphosphate (GTP) by the RasᄋGAP Protein Complex: Reaction Mechanism and Kinetic Scheme 

      Khrenova, Maria G.; Grigorenko, Bella L.; Kolomeisky, Anatoly B.; Nemukhin, Alexander V. (2015)
      Molecular mechanisms of the hydrolysis of guanosine triphosphate (GTP) to guanosine diphosphate (GDP) and inorganic phosphate (Pi) by the Ras·GAP protein complex are fully investigated by using modern modeling tools. The ...
    • Hydrophilic carbon clusters as therapeutic, high-capacity antioxidants 

      Samuel, Errol L.G.; Duong, MyLinh T.; Bitner, Brittany R.; Marcano, Daniela C.; Tour, James M.; Kent, Thomas A. (2014)
      Oxidative stress reflects an excessive accumulation of reactive oxygen species (ROS) and is a hallmark of several acute and chronic human pathologies. Although many antioxidants have been investigated, most have demonstrated ...
    • Hydroxyproline-free Single Composition ABC Collagen Heterotrimer 

      Jalan, Abhishek A.; Demeler, Borries; Hartgerink, Jeffrey D. (2013)
      Hydroxyproline plays a major role in stabilizing collagenous domains in eukaryotic organisms. Lack of this modification is associated with significant lowering in thermal stability of the collagen triple helix and may also ...
    • Hyper-generalized-gradient functionals constructed from the Lieb-Oxford bound: Implementation via local hybrids and thermochemical assessment 

      Haunschild, Robin; Odashima, Mariana M.; Scuseria, Gustavo E.; Perdew, John P.; Capelle, K. (2012)
      In 2009 Odashima and Capelle (OC) showed a way to design a correlation-only density functional that satisfies a Lieb-Oxford bound on the correlation energy, without empirical parameters and even without additional theoretical ...