Now showing items 146-165 of 476

    • Exploring the free energy landscape of nucleosome assembly 

      Zhang, B.; Zheng, W.; Papoian, G.A.; Wolynes, P.G. (2016)
      The nucleosome is the fundamental unit for packaging the genome. A detailed molecular picture for its conformational dynamics is crucial for understanding transcription and gene regulation. We investigate the disassembly ...
    • Expression platforms for producing eukaryotic proteins: a comparison ofᅠE. coliᅠcell-based and wheat germ cell-free synthesis, affinity and solubility tags, and cloning strategies 

      Aceti, David J.; Bingman, Craig A.; Wrobel, Russell L.; Frederick, Ronnie O.; Makino, Shin-ichi; Nichols, Karl W.; Sahu, Sarata C.; Bergeman, Lai F.; Blommel, Paul G.; Cornilescu, Claudia C.; Gromek, Katarzyna A.; Seder, Kory D.; Hwang, Soyoon; Primm, John G.; Sabat, Grzegorz; Vojtik, Frank C.; Volkman, Brian F.; Zolnai, Zsolt; Phillips, George N. Jr.; Markley, John L.; Fox, Brian G. (2015)
      Vectors designed for protein production in Escherichia coli and by wheat germ cell-free translation were tested using 21 well-characterized eukaryotic proteins chosen to serve as controls within the context of a structural ...
    • Extending single molecule fluorescence observation time by amplitude-modulated excitation 

      Kisley, Lydia; Chang, Wei-Shun; Cooper, David; Mansur, Andrea P.; Landes, Christy F. (2013)
      We present a hardware-based method that can improve single molecule fluorophore observation time by up to 1500% and super-localization by 47% for the experimental conditions used. The excitation was modulated using an ...
    • Facile one-pot synthesis of triphenylbismuth (V) bis(carboxylate) complexes 

      Kumar, Ish; Bhattacharya, Prateek; Whitmire, Kenton H. (2014)
      Triphenylbismuth(V) bis(carboxylates), Ph3Bi(O2CR)2 (R = 5-Br-2-OH-C6H3- (1), 2-OH-C6H4-(2), 2,6-(OH)2-C6H3- (3); 3-Me-2-NH2-C6H3- (4); Ph- (5) and Me- (6)) were obtained from the reaction of triphenylbismuth with hydrogen ...
    • Facilitation of DNA loop formation by protein–DNA non-specific interactions 

      Shin, Jaeoh; Kolomeisky, Anatoly B. (2019)
      Complex DNA topological structures, including polymer loops, are frequently observed in biological processes when protein molecules simultaneously bind to several distant sites on DNA. However, the molecular mechanisms of ...
    • Fast Step Transition and State Identification (STaSI) for Discrete Single-Molecule Data Analysis 

      Shuang, Bo; Cooper, David; Taylor, J. Nick; Kisley, Lydia; Chen, Jixin; Wang, Wenxiao; Li, Chun Biu; Komatsuzaki, Tamiki; Landes, Christy F. (2014)
      We introduce a step transition and state identification (STaSI) method for piecewise constant single-molecule data with a newly derived minimum description length equation as the objective function. We detect the step ...
    • Ferromagnetism in Graphene Nanoribbons: Split versus Oxidative Unzipped Ribbons 

      Rao, S.S.; Jammalamadaka, S. Narayana; Stesmans, A.; Moshchalkov, V.V.; van Tol, J.; Kosynkin, D.V.; Higginbotham, A.; Tour, J.M. (2012)
      Two types of graphene nanoribbons: (a) potassium-split graphene nanoribbons (GNRs), and (b) oxidative unzipped and chemically converted graphene nanoribbons (CCGNRs) were investigated for their magnetic properties using ...
    • Fluctuating mobility generation and transport in glasses 

      Wisitsorasak, Apiwat; Wolynes, Peter G. (2013)
      In the context of the random first order transition theory we use an extended mode coupling theory of the glass transition that includes activated events to account for spatiotemporal structures in rejuvenating glasses. ...
    • Fluorescence Correlation Spectroscopy Study of Protein Transport and Dynamic Interactions with Clustered-Charge Peptide Adsorbents 

      Daniels, Charlisa R.; Kisley, Lydia; Kim, Hannah; Chen, Wen-Hsiang; Poongavanam, Mohan- Vivekanandan; Reznik, Carmen; Kourentzi, Katerina; Willson, Richard C.; Landes, Christy F. (2012-08)
      Ion-exchange chromatography (IEX) relies on electrostatic interactions between the adsorbent and the adsorbate, and is used extensively in protein purification. Conventional IEX utilizes ligands that are singly charged and ...
    • Fluorinated h-BN as a magnetic semiconductor 

      Radhakrishnan, Sruthi; Das, Deya; Samanta, Atanu; de los Reyes, Carlos A.; Deng, Liangzi; Alemany, Lawrence B.; Weldeghiorghis, Thomas K.; Khabashesku, Valery N.; Kochat, Vidya; Jin, Zehua; Sudeep, Parambath M.; Martí, Angel A.; Chu, Ching-Wu; Roy, Ajit; Tiwary, Chandra Sekhar; Singh, Abhishek K.; Ajayan, Pulickel M. (2017)
      We report the fluorination of electrically insulating hexagonal boron nitride (h-BN) and the subsequent modification of its electronic band structure to a wide bandgap semiconductor via introduction of defect levels. The ...
    • From tunable core-shell nanoparticles to plasmonic drawbridges: Active control of nanoparticle optical properties 

      Byers, Chad P.; Zhang, Hui; Swearer, Dayne F.; Yorulmaz, Mustafa; Hoener, Benjamin S.; Huang, Da; Hoggard, Anneli; Chang, Wei-Shun; Mulvaney, Paul; Ringe, Emilie; Halas, Naomi J.; Nordlander, Peter; Link, Stephan; Landes, Christy F. (2015)
      The optical properties of metallic nanoparticles are highly sensitive to interparticle distance, giving rise to dramatic but frequently irreversible color changes. By electrochemical modification of individual nanoparticles ...
    • Frustration in biomolecules 

      Ferreiro, Diego U.; Komives, Elizabeth A.; Wolynes, Peter G. (2014)
      Biomolecules are the prime information processing elements of living matter. Most of these inanimate systems are polymers that compute their own structures and dynamics using as input seemingly random character strings of ...
    • Full-waveform inversion of triplicated data using a normalized-correlation-coefficient-based misfit function 

      Tao, Kai; Grand, Stephen P.; Niu, Fenglin (2017)
      In seismic full-waveform inversion (FWI), the choice of misfit function determines what information in data is used and ultimately affects the resolution of the inverted images of the Earth's structure. Misfit functions ...
    • Fundamental optical processes in armchair carbon nanotubes 

      Haroz, Erik H.; Duque, Juan G.; Tu, Xiaomin; Zheng, Ming; Walker, Angela R. Hight; Hauge, Robert H.; Doorn, Stephen K.; Kono, Junichiro (2013)
      Single-wall carbon nanotubes provide ideal model one-dimensional (1-D) condensed matter systems in which to address fundamental questions in many-body physics, while, at the same time, they are leading candidates for ...
    • Funneling and frustration in the energy landscapes of some designed and simplified proteins 

      Truong, Ha H.; Kim, Bobby L.; Schafer, Nicholas P.; Wolynes, Peter G. (2013)
      We explore the similarities and differences between the energy landscapes of proteins that have been selected by nature and those of some proteins designed by humans. Natural proteins have evolved to function as well as ...
    • Gadonanotube materials as new intracellular MRI contrast agents for stem cell labeling 

      Hernández-Rivera, Mayra; Wilson, Lon J. (2016)
      Stem cells possess great potential for different medical applications and every year more investigators join this field of study. As interest in stem cells has increased, it has become essential to track the cellsin vivo in ...
    • Generalized recovery algorithm for 3D super-resolution microscopy using rotating point spread functions 

      Shuang, Bo; Wang, Wenxiao; Shen, Hao; Tauzin, Lawrence J.; Flatebo, Charlotte; Chen, Jianbo; Moringo, Nicholas A.; Bishop, Logan D.C.; Kelly, Kevin F.; Landes, Christy F. (2016)
      Super-resolution microscopy with phase masks is a promising technique for 3D imaging and tracking. Due to the complexity of the resultant point spread functions, generalized recovery algorithms are still missing. We introduce ...
    • Geometrical confinement of Gd(DOTA) molecules within mesoporous silicon nanoconstructs for MR imaging of cancer 

      Gizzatov, Ayrat; Stigliano, Cinzia; Ananta, Jeyerama S.; Sethi, Richa; Xu, Rong; Guven, Adem; Ramirez, Maricela; Shen, Haifa; Sood, Anil; Ferrari, Mauro; Wilson, Lon J.; Liu, Xuewu; Decuzzi, Paolo (2014)
      Porous silicon has been used for the delivery of therapeutic and imaging agents in several biomedical applications. Here, mesoporous silicon nanoconstructs (SiMPs) with a discoidal shape and a sub-micrometer size (1,000 × ...
    • Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble 

      Fisher, Kaitlin M.; Haglund, Ellinor; Noel, Jeffrey K.; Hailey, Kendra L.; Onuchic, José N.; Jennings, Patricia A. (2015)
      Interleukin-33 (IL-33) is currently the focus of multiple investigations into targeting pernicious inflammatory disorders. This mediator of inflammation plays a prevalent role in chronic disorders such as asthma, rheumatoid ...
    • Gold coated iron phosphide core–shell structures 

      Kelly, Anna T.; Filgueira, Carly S.; Schipper, Desmond E.; Halas, Naomi J.; Whitmire, Kenton H. (2017)
      Core–shell particles Fe2P@Au have been prepared beginning with Fe2P nanorods, nanocrosses and nanobundles prepared from the solvothermal decomposition of H2Fe3(CO)9(μ3-PtBu). Iron phosphide structures can be produced from ...