Recent Submissions

  • Biocompatibility of reduced graphene oxide nanoscaffolds following acute spinal cord injury in rats 

    Palejwala, Ali H.; Fridley, Jared S.; Mata, Javier A.; Samuel, Errol L.G.; Luerssen, Thomas G.; Perlaky, Laszlo; Kent, Thomas A.; Tour, James M.; Jea, Andrew (2016)
    Background: Graphene has unique electrical, physical, and chemical properties that may have great potential as a bioscaffold for neuronal regeneration after spinal cord injury. These nanoscaffolds have previously been shown ...
  • Bi-Phasic photocatalytic particles prepared by sequential layer depositions for water cleaning and purification 

    Gomez, Virginia; Rome, Bertrand; Barron, Andrew R.; Dunnill, Charles W. (2016)
    Bi-phasic photocatalyic particles have been prepared in the form of Janus-like structures (bi-phasic materials with two distinct properties on opposing sides of the particle) using a new synthetic procedure consisting of ...
  • Reader domain specificity and lysine demethylase-4 family function 

    Su, Zhangli; Wang, Fengbin; Lee, Jin-Hee; Stephens, Kimberly E.; Papazyan, Romeo; Voronina, Ekaterina; Krautkramer, Kimberly A.; Raman, Ana; Thorpe, Jeremy J.; Boersma, Melissa D.; Kuznetsov, Vyacheslav I.; Miller, Mitchell D.; Taverna, Sean D.; Phillips, George N. Jr.; Denu, John M. (2016)
    The KDM4 histone demethylases are conserved epigenetic regulators linked to development, spermatogenesis and tumorigenesis. However, how the KDM4 family targets specific chromatin regions is largely unknown. Here, an ...
  • Molecular stripping, targets and decoys as modulators of oscillations in the NF-κB/IκBα/DNA genetic network 

    Wang, Zhipeng; Potoyan, Davit A.; Wolynes, Peter G. (2016)
    Eukaryotic transcription factors in the NF-κB family are central components of an extensive genetic network that activates cellular responses to inflammation and to a host of other external stressors. This network consists ...
  • Stargazin Modulation of AMPA Receptors 

    Shaikh, Sana A.; Dolino, Drew M.; Lee, Garam; Chatterjee, Sudeshna; MacLean, David M.; Flatebo, Charlotte; Landes, Christy F.; Jayaraman, Vasanthi (2016)
    Fast excitatory synaptic signaling in the mammalian brain is mediated by AMPA-type ionotropic glutamate receptors. In neurons, AMPA receptors co-assemble with auxiliary proteins, such as stargazin, which can markedly alter ...
  • The opposite effects of sodium and potassium cations on water dynamics 

    Zhang, Qiang; Chen, Hailong; Wu, Tianmin; Jin, Tan; Pan, Zhijun; Zheng, Junrong; Gao, Yiqin; Zhuang, Wei (2017)
    Water rotational dynamics in NaSCN and KSCN solutions at a series of concentrations are investigated using femtosecond infrared spectroscopy and theory. Femtosecond infrared measurements, consistent with previous NMR ...
  • (n,m)-Specific Absorption Cross Sections of Single-Walled Carbon Nanotubes Measured by Variance Spectroscopy 

    Sanchez, Stephen R.; Bachilo, Sergei M.; Kadria-Vili, Yara; Lin, Ching-Wei; Weisman, R. Bruce (2016)
    A new method based on variance spectroscopy has enabled the determination of absolute absorption cross sections for the first electronic transition of 12 (n,m) structural species of semiconducting single-walled carbon ...
  • Surface-initiated growth of copper using isonicotinic acid-functionalized aluminum oxide surfaces 

    Gowenlock, Cathren E.; Gomez, Virginia; McGettrick, James D.; Andreoli, Enrico; Barron, Andrew R. (2016)
    Isonicotinate self-assembled monolayers (SAM) were prepared on alumina surfaces (A) using isonicotinic acid (iNA). These functionalized layers (iNA-A) were used for the seeded growth of copper films (Cu-iNA-A) by hydrazine ...
  • Photo-induced force mapping of plasmonic nanostructures 

    Tumkur, Thejaswi U.; Yang, Xiao; Cerjan, Benjamin; Halas, Naomi J.; Nordlander, Peter; Thomann, Isabell (2016)
    The ability to image the optical near-fields of nanoscale structures, map their morphology and concurrently obtain spectroscopic information, all with high spatiotemporal resolution, is a highly sought-after technique in ...
  • Improving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm 

    He, Hongxing; Fang, Hengrui; Miller, Mitchell D.; Phillips, George N. Jr.; Su, Wu-Pei (2016)
    An iterative transform method proposed previously for direct phasing of high-solvent-content protein crystals is employed for enhancing the molecular-replacement (MR) algorithm in protein crystallography. Target structures ...
  • Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis 

    Singh, Shanteri; Kim, Youngchang; Wang, Fengbin; Bigelow, Lance; Endres, Michael; Kharel, Madan K.; Babnigg, Gyorgy; Bingman, Craig A.; Joachimiak, Andrzej; Thorson, Jon S.; Phillips, George N. Jr. (2015)
    AT2433 from Actinomadura melliaura is an indolocarbazole antitumor antibiotic structurally distinguished by its unique aminodideoxypentose-containing disaccharide moiety. The corresponding sugar nucleotide-based biosynthetic ...
  • Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trialsᅠ 

    Speight, Paul M.; Abram, Timothy J.; Floriano, Pierre N.; James, Robert; Vick, Julie; Thornhill, Martin H.; Murdoch, Craig; Freeman, Christine; Hegarty, Anne M.; D’Apice, Katy; Kerr, A. Ross; Phelan, Joan; Corby, Patricia; Khouly, Ismael; Vigneswaran, Nadarajah; Bouquot, Jerry; Demian, Nagi M.; Weinstock, Y. Etan; Redding, Spencer W.; Rowan, Stephanie; Yeh, Chih-Ko; McGuff, H. Stan; Miller, Frank R.; McDevitt, John T. (2015)
    Objective: Interobserver agreement in the context of oral epithelial dysplasia (OED) grading has been notoriously unreliable and can impose barriers for developing new molecular markers and diagnostic technologies. This ...
  • Total Synthesis and Structural Revision of Antibiotic CJ-16,264 

    Nicolaou, K.C.; Shah, Akshay A.; Korman, Henry; Khan, Tabrez; Shi, Lei; Worawalai, Wisuttaya; Theodorakis, Emmanuel A. (2015)
    The total synthesis and structural revision of antibiotic CJ-16,264 is described. Starting with citronellal, the quest for the target molecule featured a novel bis-transannular Diels-Alder reaction that casted stereoselectively ...
  • Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases 

    Wang, Fengbin; Singh, Shanteri; Xu, Weijun; Helmich, Kate E.; Miller, Mitchell D.; Cao, Hongnan; Bingman, Craig A.; Thorson, Jon S.; Phillips, George N. Jr. (2015)
    Sugar aminotransferases (SATs) are an important class of tailoring enzymes that catalyze the 5'-pyridoxal phosphate (PLP)-dependent stereo- and regiospecific installation of an amino group from an amino acid donor (typically ...
  • Enhancement of performance in porous bead-based microchip sensors: effects of chip geometry on bio-agent capture 

    Kulla, Eliona; Chou, Jie; Simmons, Glennon; Wong, Jorge; McRae, Michael P.; Patel, Rushi; Floriano, Pierre N.; Christodoulides, Nicolaos; Leach, Robin J.; Thompson, Ian M.; McDevitt, John T. (2015)
    Measuring low concentrations of clinically-important biomarkers using porous bead-based lab-on-a-chip (LOC) platforms is critical for the successful implementation of point-of-care (POC) devices. One way to meet this ...
  • Biodegradable, phosphate-containing, dual-gelling macromers for cellular delivery in bone tissue engineering 

    Watson, Brendan M.; Vo, Tiffany N.; Tatara, Alexander M.; Shah, Sarita R.; Scott, David W.; Engel, Paul S.; Mikos, Antonios G. (2015)
    Injectable, biodegradable, dual-gelling macromer solutions were used to encapsulate mesenchymal stem cells (MSCs) within stable hydrogels when elevated to physiologic temperature. Pendant phosphate groups were incorporated ...
  • Detecting the Biopolymer Behavior of Graphene Nanoribbons in Aqueous Solution 

    Wijeratne, Sithara S.; Penev, Evgeni S.; Lu, Wei; Li, Jingqiang; Duque, Amanda L.; Yakobson, Boris I.; Tour, James M.; Kiang, Ching-Hwa (2016)
    Graphene nanoribbons (GNR), can be prepared in bulk quantities for large-area applications by reducing the product from the lengthwise oxidative unzipping of multiwalled carbon nanotubes (MWNT). Recently, the biomaterials ...
  • Ultrafast formation of interlayer hot excitons in atomically thin MoS2/WS2ᅠheterostructures 

    Chen, Hailong; Wen, Xiewen; Zhang, Jing; Wu, Tianmin; Gong, Yongji; Zhang, Xiang; Yuan, Jiangtan; Yi, Chongyue; Lou, Jun; Ajayan, Pulickel M.; Zhuang, Wei; Zhang, Guangyu; Zheng, Junrong (2016)
    Van der Waals heterostructures composed of two-dimensional transition-metal dichalcogenides layers have recently emerged as a new family of materials, with great potential for atomically thin opto-electronic and photovoltaic ...
  • Generalized recovery algorithm for 3D super-resolution microscopy using rotating point spread functions 

    Shuang, Bo; Wang, Wenxiao; Shen, Hao; Tauzin, Lawrence J.; Flatebo, Charlotte; Chen, Jianbo; Moringo, Nicholas A.; Bishop, Logan D.C.; Kelly, Kevin F.; Landes, Christy F. (2016)
    Super-resolution microscopy with phase masks is a promising technique for 3D imaging and tracking. Due to the complexity of the resultant point spread functions, generalized recovery algorithms are still missing. We introduce ...
  • Singlet-paired coupled cluster theory for open shells 

    Gomez, John A.; Henderson, Thomas M.; Scuseria, Gustavo E. (2016)
    Restricted single-reference coupled cluster theory truncated to single and double excitations accurately describes weakly correlated systems, but often breaks down in the presence of static or strongcorrelation. Good coupled ...

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