Now showing items 1-2 of 2
Structure analysis of free and bound states of an RNA aptamer against ribosomal protein S8 from Bacillus anthracis
(Oxford University Press, 2014)
Several protein-targeted RNA aptamers have been identified for a variety of applications and although the affinities of numerous protein-aptamer complexes have been determined, the structural details of these complexes ...
Total Synthesis of Viridicatumtoxin B and Analogues Thereof: Strategy Evolution, Structural Revision, and Biological Evaluation
(American Chemical Society, 2014)
The details of the total synthesis of viridicatumtoxin B (1) are described. Initial synthetic strategies toward this intriguing tetracycline antibiotic resulted in the development of key alkylation and Lewis acid-mediated ...