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Three-dimensional in vitro tumor models for cancer research and drug evaluation
Cancer occurs when cells acquire genomic instability and inflammation, produce abnormal levels of epigenetic factors/proteins and tumor suppressors, reprogram the energy metabolism and evade immune destruction, leading to ...
A hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics
Three-dimensional (3D) tissue-engineered tumor models have the potential to bridge the gap between monolayer cultures and patient-derived xenografts for the testing of nanoparticle (NP)-based cancer therapeutics. In this ...