Now showing items 1-4 of 4

    • Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1 

      Tamir, Sagi; Rotem-Bamberger, Shahar; Katz, Chen; Morcos, Faruck; Hailey, Kendra L.; Zuris, John A.; Wang, Charles; Conlan, Andrea R.; Lipper, Colin H.; Paddock, Mark L.; Mittler, Ron; Onuchic, José N.; Jennings, Patricia A.; Friedler, Assaf; Nechushtai, Rachel (2014)
      Life requires orchestrated control of cell proliferation, cell maintenance, and cell death. Involved in these decisions are protein complexes that assimilate a variety of inputs that report on the status of the cell and ...
    • Interactions between mitoNEET and NAF-1 in cells 

      Karmi, Ola; Holt, Sarah H.; Song, Luhua; Tamir, Sagi; Luo, Yuting; Bai, Fang; Adenwalla, Ammar; Darash-Yahana, Merav; Sohn, Yang-Sung; Jennings, Patricia A.; Azad, Rajeev K.; Onuchic, José N.; Morcos, Faruck; Nechushtai, Rachel; Mittler, Ron (2017)
      The NEET proteins mitoNEET (mNT) and nutrient-deprivation autophagy factor-1 (NAF-1) are required for cancer cell proliferation and resistance to oxidative stress. NAF-1 and mNT are also implicated in a number of other ...
    • NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth 

      Sohn, Yang-Sung; Tamir, Sagi; Song, Luhua; Michaeli, Dorit; Matouk, Imad; Conlan, Andrea R.; Harir, Yael; Holt, Sarah H.; Shulaev, Vladimir; Paddock, Mark L.; Hochberg, Abraham; Cabanchick, Ioav Z.; Onuchic, José N.; Jennings, Patricia A.; Nechushtai, Rachel; Mittler, Ron (2013)
      Mitochondria are emerging as important players in the transformation process of cells, maintaining the biosynthetic and energetic capacities of cancer cells and serving as one of the primary sites of apoptosis and autophagy ...
    • The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells 

      Iosub-Amir, Anat; Bai, Fang; Sohn, Yang-Sung; Song, Luhua; Tamir, Sagi; Marjault, Henri-Baptiste; Mayer, Guy; Karmi, Ola; Jennings, Patricia A.; Mittler, Ron; Onuchic, José N.; Friedler, Assaf; Nechushtai, Rachel (2019)