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Total Synthesis of Δ12-Prostaglandin J3, a Highly Potent and Selective Antileukemic Agent
(Wiley, 2014)
A catalytic asymmetric total synthesis of the potent and selective antileukemic Δ12-prostaglandin J3 (Δ12-PGJ3) is described. The convergent synthesis proceeded through intermediates 2 and 3, constructed enantioselectively ...