Now showing items 25-44 of 124

  • Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse 

    Choi, Mi-Ran; Bardhan, Rizia; Stanton-Maxey, Katie J.; Badve, Sunil; Nakshatri, Harikrishna; Stantz, Keith M.; Cao, Ning; Halas, Naomi J.; Clare, Susan E. (2012)
    As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood–brain barrier (BBB) represents a major ...
  • Directed motion of periodically driven molecular motors: A graph-theoretical approach 

    Akimov, Alexey V.; Mandal, Dibyendu; Chernyak, Vladimir Y.; Sinitsyn, Nikolai A. (2013-01-11)
    We propose a numerical algorithm for calculation of quantized directed motion of a stochastic system of interacting particles induced by periodic changes of control parameters on the graph of microstates. As a main ...
  • Discrete Kinetic Models from Funneled Energy Landscape Simulations 

    Schafer, Nicholas P.; Hoffman, Ryan M.B.; Burger, Anat; Craig, Patricio O.; Komives, Elizabeth A. (2012-12-12)
    A general method for facilitating the interpretation of computer simulations of protein folding with minimally frustrated energy landscapes is detailed and applied to a designed ankyrin repeat protein (4ANK). In the method, ...
  • Distributed Cooperative Communications in Wireless Networks 

    Khojastepour, Mohammad (2005-01-01)
    The primary challenge in communication over wireless networks, unlike wireline networks, is the existence of interference and channel variations (fading). Having more users at higher data rates means that current ...
  • Dye-Assisted Gain of Strongly Confined Surface Plasmon Polaritons in Silver Nanowires 

    Paul, Aniruddha; Zhen, Yu-Rong; Wang, Yi; Chang, Wei-Shun; Xia, Younan; Nordlander, Peter; Link, Stephan (2014)
    Subwavelength confinement and active control of light is essential for nanoscale communication devices at visible frequencies that support large bandwidths.[1-5] Noble-metal nanostructures present an excellent platform for ...
  • The Emergence of the Structure of the Molecule and the Art of Its Synthesis 

    Nicolaou, K.C. (2013)
    At the core of the science of chemistry lie the structure of the molecule, the art of its synthesis, and the design of function within it. These attributes elevate chemistry to an essential, indispensable, and powerful ...
  • The endeavor of total synthesis and its impact on chemistry, biology and medicine 

    Nicolaou, K.C.; Hale, Christopher R.H. (2014)
    The synthesis of urea in 1828 set in motion the discipline of organic synthesis in general and of total synthesis in particular, the art and science of synthesizing natural products, the molecules of living nature. Early ...
  • Enhanced MRI relaxivity of Gd3+-based contrast agents geometrically confined within porous nanoconstructs 

    Sethi, Richa; Ananta, Jeyarama S.; Karmonik, Christof; Zhong, Meng; Fung, Steve H.; Liu, Xuewu; Li, King; Ferrari, Mauro; Wilson, Lon J.; Decuzzi, Paolo (2012)
    Gadolinium chelates, which are currently approved for clinical MRI use, provide relaxivities well below their theoretical limit, and they also lack tissue specificity. Recently, the geometrical confinement of Gd3+-based ...
  • Equilibrium at the edge and atomistic mechanisms of graphene growth 

    Artyukhov, Vasilii I.; Liu, Yuanyue; Yakobson, Boris I. (2012-09-18)
    The morphology of graphene is crucial for its applications, yet an adequate theory of its growth is lacking: It is either simplified to a phenomenological-continuum level or is overly detailed in atomistic simulations, ...
  • Experimental realization of crossover in shape and director field of nematic tactoids 

    Jamali, Vida; Behabtu, Natnael; Senyuk, Bohdan; Lee, J. Alex; Smalyukh, Ivan I.; van der Schoot, Paul; Pasquali, Matteo (2015)
    Spindle-shaped nematic droplets (tactoids) form in solutions of rod-like molecules at the onset of the liquid crystalline phase. Their unique shape and internal structure result from the interplay of the elastic deformation ...
  • Exploiting Predictable Observer Mobility for Power Efficient Sensor Network Communication 

    Chakrabarti, Arnab (2003-04-20)
    This thesis introduces techniques that exploit predictable mobility of the observer (data sink) to reduce communication range, thereby saving power in wireless sensor networks (WSNs). The movement of public transport ...
  • Extending single molecule fluorescence observation time by amplitude-modulated excitation 

    Kisley, Lydia; Chang, Wei-Shun; Cooper, David; Mansur, Andrea P.; Landes, Christy F. (2013)
    We present a hardware-based method that can improve single molecule fluorophore observation time by up to 1500% and super-localization by 47% for the experimental conditions used. The excitation was modulated using an ...
  • Facile one-pot synthesis of triphenylbismuth (V) bis(carboxylate) complexes 

    Kumar, Ish; Bhattacharya, Prateek; Whitmire, Kenton H. (2014)
    Triphenylbismuth(V) bis(carboxylates), Ph3Bi(O2CR)2 (R = 5-Br-2-OH-C6H3- (1), 2-OH-C6H4-(2), 2,6-(OH)2-C6H3- (3); 3-Me-2-NH2-C6H3- (4); Ph- (5) and Me- (6)) were obtained from the reaction of triphenylbismuth with hydrogen ...
  • Fluorescence Correlation Spectroscopy Study of Protein Transport and Dynamic Interactions with Clustered-Charge Peptide Adsorbents 

    Daniels, Charlisa R.; Kisley, Lydia; Kim, Hannah; Chen, Wen-Hsiang; Poongavanam, Mohan- Vivekanandan; Reznik, Carmen; Kourentzi, Katerina; Willson, Richard C.; Landes, Christy F. (2012-08)
    Ion-exchange chromatography (IEX) relies on electrostatic interactions between the adsorbent and the adsorbate, and is used extensively in protein purification. Conventional IEX utilizes ligands that are singly charged ...
  • Frustration in biomolecules 

    Ferreiro, Diego U.; Komives, Elizabeth A.; Wolynes, Peter G. (2014)
    Biomolecules are the prime information processing elements of living matter. Most of these inanimate systems are polymers that compute their own structures and dynamics using as input seemingly random character strings of ...
  • Fundamental optical processes in armchair carbon nanotubes 

    Haroz, Erik H.; Duque, Juan G.; Tu, Xiaomin; Zheng, Ming; Walker, Angela R. Hight; Hauge, Robert H.; Doorn, Stephen K.; Kono, Junichiro (2013)
    Single-wall carbon nanotubes provide ideal model one-dimensional (1-D) condensed matter systems in which to address fundamental questions in many-body physics, while, at the same time, they are leading candidates for ...
  • Funneling and frustration in the energy landscapes of some designed and simplified proteins 

    Truong, Ha H.; Kim, Bobby L.; Schafer, Nicholas P.; Wolynes, Peter G. (2013)
    We explore the similarities and differences between the energy landscapes of proteins that have been selected by nature and those of some proteins designed by humans. Natural proteins have evolved to function as well as ...
  • High ionic strength narrows the population of sites participating in protein ion-exchange adsorption: A single-molecule study 

    Kisley, Lydia; Chen, Jixin; Mansur, Andrea P.; Dominguez-Medina, Sergio; Kulla, Eliona; Kang, Marci; Shuang, Bo; Kourentzi, Katerina; Poongavanam, Mohan-Vivekanandan; Dhamane, Sagar; Willson, Richard C.; Landes, Christy F. (2014)
    The retention and elution of proteins in ion-exchange chromatography is routinely controlled by adjusting the mobile phase salt concentration. It has repeatedly been observed, as judged from adsorption isotherms, that the ...
  • High Precision Fractionator for use with Density Gradient Ultracentrifugation 

    Kadria-Vili, Yara; Canning, Griffin; Bachilo, Sergei M.; Weisman, R. Bruce (2014)
    The recent application of density gradient ultracentrifugation (DGU) for structural sorting of single-walled carbon nanotube samples has created a need for highly selective extraction of closely spaced layers formed in the ...
  • High-Ampacity Power Cables of Tightly-Packed and Aligned Carbon Nanotubes 

    Wang, Xuan; Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Pasquali, Matteo; Kono, Junichiro (2014)
    The current-carrying capacity (CCC), or ampacity, of highly-conductive, light, and strong carbon nanotube (CNT) fibers is characterized by measuring their failure current density (FCD) and continuous current rating (CCR) ...