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  • Super-Resolution mbPAINT for Optical Localization of Single-Stranded DNA 

    Chen, Jixin; Bremauntz, Alberto; Kisley, Lydia; Shuang, Bo; Landes, Christy F. (2013)
    We demonstrate the application of superlocalization microscopy to identify sequence-specific portions of single-stranded DNA (ssDNA) with sequence resolution of 50 nucleotides, corresponding to a spatial resolution of 30 ...
  • Physical removal of metallic carbon nanotubes from nanotube network devices using a thermal and fluidic process 

    Ford, Alexandra C.; Shaughnessy, Michael; Wong, Bryan M.; Kane, Alexander A.; Kuznetsov, Oleksandr V.; Krafcik, Karen L.; Billups, W.E.; Hauge, Robert H.; Léonard, François (2013)
    Electronic and optoelectronic devices based on thin films of carbon nanotubes are currently limited by the presence of metallic nanotubes. Here we present a novel approach based on nanotube alkyl functionalization to ...
  • Synthesis and Characterization of Injectable, Biodegradable, Phosphate-Containing, Chemically Cross-Linkable, Thermoresponsive Macromers for Bone Tissue Engineering 

    Watson, Brendan M.; Kasper, F. Kurtis; Engel, Paul S.; Mikos, Antonios G. (2014)
    Novel, injectable, biodegradable macromer solutions that form hydrogels when elevated to physiologic temperature via a dual chemical and thermo-gelation were fabricated and characterized. A thermogelling, poly(N-isopropy ...
  • Au Nanomatryoshkas as Efficient Near-Infrared Photothermal Transducers for Cancer Treatment: Benchmarking against Nanoshells 

    Ayala-Orozco, Ciceron; Urban, Cordula; Knight, Mark W.; Urban, Alexander Skyrme; Neumann, Oara; Bishnoi, Sandra W.; Mukherjee, Shaunak; Goodman, Amanda M.; Charron, Heather; Mitchell, Tamika; Shea, Martin; Roy, Ronita; Nanda, Sarmistha; Schiff, Rachel; Halas, Naomi J.; Joshi, Amit (2014)
    Au nanoparticles with plasmon resonances in the near-infrared (NIR) region of the spectrum efficiently convert light into heat, a property useful for the photothermal ablation of cancerous tumors subsequent to nanoparticle ...
  • Bismuth@US-tubes as a potential contrast agent for X-ray imaging applications 

    Rivera, Eladio J.; Tran, Lesa A.; Hernández-Rivera, Mayra; Yoon, Diana; Mikos, Antonios G.; Rusakova, Irene A.; Cheong, Benjamin Y.; Cabreira-Hansen, Maria da Graça; Willerson, James T.; Perin, Emerson C.; Wilson, Lon J. (2013)
    The encapsulation of bismuth as BiOCl/Bi2O3 within ultra-short (ca. 50 nm) single-walled carbon nanocapsules (US-tubes) has been achieved. The Bi@US-tubes have been characterized by high-resolution transmission electron ...
  • High ionic strength narrows the population of sites participating in protein ion-exchange adsorption: A single-molecule study 

    Kisley, Lydia; Chen, Jixin; Mansur, Andrea P.; Dominguez-Medina, Sergio; Kulla, Eliona; Kang, Marci; Shuang, Bo; Kourentzi, Katerina; Poongavanam, Mohan-Vivekanandan; Dhamane, Sagar; Willson, Richard C.; Landes, Christy F. (2014)
    The retention and elution of proteins in ion-exchange chromatography is routinely controlled by adjusting the mobile phase salt concentration. It has repeatedly been observed, as judged from adsorption isotherms, that the ...
  • Remotely triggered cisplatin release from carbon nanocapsules by radiofrequency fields 

    Raoof, Mustafa; Cisneros, Brandon T.; Guven, Adem; Corr, Stuart J.; Wilson, Lon J.; Curley, Steven A. (2013)
    The efficacy of nanoparticle-mediated drug delivery is limited by its peri-vascular sequestration, thus necessitating a strategy to trigger drug release from such intra-tumoral nanocarrier-drug depots. In our efforts to ...
  • Extending single molecule fluorescence observation time by amplitude-modulated excitation 

    Kisley, Lydia; Chang, Wei-Shun; Cooper, David; Mansur, Andrea P.; Landes, Christy F. (2013)
    We present a hardware-based method that can improve single molecule fluorophore observation time by up to 1500% and super-localization by 47% for the experimental conditions used. The excitation was modulated using an ...
  • Charge-Dependent Transport Switching of Single Molecular Ions in a Weak Polyelectrolyte Multilayer 

    Tauzin, Lawrence J.; Shuang, Bo; Kisley, Lydia; Mansur, Andrea P.; Chen, Jixin; de Leon, Al; Advincula, Rigoberto C.; Landes, Christy F. (2014)
    The tunable nature of weak polyelectrolyte multilayers makes them ideal candidates for drug loading and delivery, water filtration, and separations, yet the lateral transport of charged molecules in these systems remains ...
  • Experimental realization of crossover in shape and director field of nematic tactoids 

    Jamali, Vida; Behabtu, Natnael; Senyuk, Bohdan; Lee, J. Alex; Smalyukh, Ivan I.; van der Schoot, Paul; Pasquali, Matteo (2015)
    Spindle-shaped nematic droplets (tactoids) form in solutions of rod-like molecules at the onset of the liquid crystalline phase. Their unique shape and internal structure result from the interplay of the elastic deformation ...
  • Tuning the acoustic frequency of a gold nanodisk through its adhesion layer 

    Chang, Wei-Shun; Wen, Fangfang; Chakraborty, Debadi; Su, Man-Nung; Zhang, Yue; Shuang, Bo; Nordlander, Peter; Sader, John E.; Halas, Naomi J.; Link, Stephan (2015)
    To fabricate robust metallic nanostructures with top-down patterning methods such as electron-beam lithography, an initial nanometer-scale layer of a second metal is deposited to promote adhesion of the metal of interest. ...
  • Operating principles of Notch–Delta–Jagged module of cell–cell communication 

    Jolly, Mohit Kumar; Boareto, Marcelo; Lu, Mingyang; Onuchic, José N.; Clementi, Cecilia; Ben-Jacob, Eshel (2015)
    Notch pathway is an evolutionarily conserved cell–cell communication mechanism governing cell-fate during development and tumor progression. It is activated when Notch receptor of one cell binds to either of its ligand—Delta ...
  • High-Ampacity Power Cables of Tightly-Packed and Aligned Carbon Nanotubes 

    Wang, Xuan; Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Pasquali, Matteo; Kono, Junichiro (2014)
    The current-carrying capacity (CCC), or ampacity, of highly-conductive, light, and strong carbon nanotube (CNT) fibers is characterized by measuring their failure current density (FCD) and continuous current rating (CCR) ...
  • Single-Particle Absorption Spectroscopy by Photothermal Contrast 

    Yorulmaz, Mustafa; Nizzero, Sara; Hoggard, Anneli; Wang, Lin-Yung; Cai, Yiyu; Su, Man-Nung; Chang, Wei-Shun; Link, Stephan (2015)
    Removing effects of sample heterogeneity through single-molecule and single-particle techniques has advanced many fields. While background free luminescence and scattering spectroscopy is widely used, recording the absorption ...
  • Structure-Dependent Thermal Defunctionalization of Single-Walled Carbon Nanotubes 

    Ghosh, Saunab; Wei, Fang; Bachilo, Sergei M.; Hauge, Robert H.; Billups, W.E.; Weisman, R. Bruce (2015)
    Covalent sidewall functionalization of single-walled carbon nanotubes (SWCNTs) is an important tool for tailoring their properties for research purposes and applications. In this study, SWCNT samples were first functionalized ...
  • Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors 

    Vohidov, Farrukh; Knudsen, Sarah E.; Leonard, Paul G.; Ohata, Jun; Wheadon, Michael J.; Popp, Brian V.; Ladbury, John E.; Ball, Zachary T. (2015)
    Src-family kinases (SFKs) play important roles in human biology and are key drug targets as well. However, achieving selective inhibition of individual Src-family kinases is challenging due to the high similarity within ...
  • Structural chemistry of fluoride and oxofluoride complexes of titanium(IV) 

    Davidovich, Ruven L.; Marinin, Dmitry V.; Stavila, Vitalie; Whitmire, Kenton H. (2015)
    The crystal structures of 119 fluoride and oxofluoride complexes of titanium(IV) (88 fluoride and 31 oxofluoride compounds) published to date have been analyzed and reviewed. Depending on the degree and nature of the ...
  • Aluminum Nanocrystals 

    McClain, Michael J.; Schlather, Andrea E.; Ringe, Emilie; King, Nicholas S.; Liu, Lifei; Manjavacas, Alejandro; Knight, Mark W.; Kumar, Ish; Whitmire, Kenton; Everitt, Henry O.; Nordlander, Peter; Halas, Naomi J. (2015)
    We demonstrate the facile synthesis of high purity aluminum nanocrystals over a range of controlled sizes from 70 to 220 nm diameter with size control achieved through a simple modification of solvent ratios in the reaction ...
  • The Role of Multifilament Structures and Lateral Interactions in Dynamics of Cytoskeleton Proteins and Assemblies 

    Li, Xin; Kolomeisky, Anatoly B. (2015)
    Microtubules and actin filaments are biopolymer molecules that are major components of cytoskeleton networks in biological cells. They play important roles in supporting fundamental cellular processes such as cell division, ...
  • The Surprising in Vivo Instability of Near-IR-Absorbing Hollow Au-Ag Nanoshells 

    Goodman, Amanda M.; Cao, Yang; Urban, Cordula; Neumann, Oara; Ayala-Orozco, Ciceron; Knight, Mark W.; Joshi, Amit; Nordlander, Peter; Halas, Naomi J. (2014)
    Photothermal ablation based on resonant illumination of near-infrared-absorbing noble metal nanoparticles that have accumulated in tumors is a highly promising cancer therapy, currently in multiple clinical trials. A crucial ...

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