Now showing items 1-2 of 2

    • Coevolutionary signals across protein lineages help capture multiple protein conformations 

      Morcos, Faruck; Jana, Biman; Hwa, Terence; Onuchic, José N. (2013)
      A long-standing problem in molecular biology is the determination of a complete functional conformational landscape of proteins. This includes not only proteins’ native structures, but also all their respective functional ...
    • Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1 

      Tamir, Sagi; Rotem-Bamberger, Shahar; Katz, Chen; Morcos, Faruck; Hailey, Kendra L.; Zuris, John A.; Wang, Charles; Conlan, Andrea R.; Lipper, Colin H.; Paddock, Mark L.; Mittler, Ron; Onuchic, José N.; Jennings, Patricia A.; Friedler, Assaf; Nechushtai, Rachel (2014)
      Life requires orchestrated control of cell proliferation, cell maintenance, and cell death. Involved in these decisions are protein complexes that assimilate a variety of inputs that report on the status of the cell and ...