Browsing Statistics Publications by Title
Now showing items 89-100 of 100
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Stochastic hypothesis of transition from inborn neutropenia to AML: interactions of cell population dynamics and population genetics
(2013)We present a stochastic model of driver mutations in the transition from severe congenital neutropenia to myelodysplastic syndrome to acute myeloid leukemia (AML). The model has the form of a multitype branching process.We ... -
Temporal and spectral characteristics of dynamic functional connectivity between resting-state networks reveal information beyond static connectivity
(2018)Estimation of functional connectivity (FC) has become an increasingly powerful tool for investigating healthy and abnormal brain function. Static connectivity, in particular, has played a large part in guiding conclusions ... -
The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: from big data to big analytical tools
(2017-10-03)Abstract The 2016 International Conference on Intelligent Biology and Medicine (ICIBM 2016) was held on December 8–10, 2016 in Houston, Texas, USA. ICIBM included eight scientific sessions, four tutorials, ... -
The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: summary and innovation in genomics
(2017-10-03)Abstract In this editorial, we first summarize the 2016 International Conference on Intelligent Biology and Medicine (ICIBM 2016) that was held on December 8–10, 2016 in Houston, Texas, USA, and then briefly ... -
The role of interventions in the cancer evolution–an evolutionary games approach
(2019)We propose to endow evolutionary game models with changes of the phenotypes adjustment during the transient generations performed by the parameters in the payo matrix which determine the fitness resulting from di erent ... -
The value of foresight
(2017)Suppose you have one unit of stock, currently worth 1, which you must sell before time . The Optional Sampling Theorem tells us that whatever stopping time we choose to sell, the expected discounted value we get when we ... -
Time-dependence of graph theory metrics in functional connectivity analysis
(2016)Brain graphs provide a useful way to computationally model the network structure of the connectome, and this has led to increasing interest in the use ofﾠgraph theoryﾠto quantitate and investigate the topological characteristics ... -
Using community level strategies to reduce asthma attacks triggered by outdoor air pollution: a case crossover analysis
(2014)Evidence indicates that asthma attacks can be triggered by exposure to ambient air pollutants, however, detailed pollution information is missing from asthma action plans. Asthma is commonly associated with four criteria ... -
Variant interpretation through Bayesian fusion of frequency and genomic knowledge
(2015)Variant interpretation is a central challenge in genomic medicine. A recent study demonstrates the power of Bayesian statistical approaches to improve interpretation of variants in the context of specific genes and syndromes. ... -
A visual and curatorial approach to clinical variant prioritization and disease gene discovery in genome-wide diagnostics
(2016)Background: Genome-wide data are increasingly important in the clinical evaluation of human disease. However, the large number of variants observed in individual patients challenges the efficiency and accuracy of diagnostic ... -
Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-RiskTP53ﾠMutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence
(2015)Although cisplatin has played a role in "standard-of-care" multimodality therapy for patients with advanced squamous cell carcinoma of the head and neck (HNSCC), the rate of treatment failure remains particularly high for ... -
XMRF: an R package to fit Markov Networks to high-throughput genetics data
(2016)Abstract Background Technological advances in medicine have led to a rapid proliferation of high-throughput “omics” data. Tools to mine this data and discover disrupted ...
