Now showing items 21-30 of 47
Total Synthesis of Viridicatumtoxin B and Analogues Thereof: Strategy Evolution, Structural Revision, and Biological Evaluation
(American Chemical Society, 2014)
The details of the total synthesis of viridicatumtoxin B (1) are described. Initial synthetic strategies toward this intriguing tetracycline antibiotic resulted in the development of key alkylation and Lewis acid-mediated ...
An HMM-Based Comparative Genomic Framework for Detecting Introgression in Eukaryotes
(Public Library of Science, 2014)
One outcome of interspecific hybridization and subsequent effects of evolutionary forces is introgression, which is the integration of genetic material from one species into the genome of an individual in another species. ...
Adaptation of Enterococcus faecalis to Daptomycin Reveals an Ordered Progression to Resistance
(American Society for Microbiology, 2013)
With increasing numbers of hospital-acquired antibiotic resistant infections each year and staggering health care costs, there is a clear need for new antimicrobial agents, as well as novel strategies to extend their ...
Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication
(BioMed Central, 2014)
Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral ...
Species-specific defence responses facilitate conspecifics and inhibit heterospecifics in above-belowground herbivore interactions
(Macmillan Publishers Limited, 2014)
Conspecific and heterospecific aboveground and belowground herbivores often occur together in nature and their interactions may determine community structure. Here we show how aboveground adults and belowground larvae of ...
Computational approaches to species phylogeny inference and gene tree reconciliation
An intricate relationship exists between gene trees and species phylogenies, due to evolutionary processes that act on the genes within and across the branches of the species phylogeny. From an analytical perspective, gene ...
Genetic variation in anti-herbivore chemical defences in an invasive plant
(British Ecological Society, 2012)
Does phylogeny matter? Assessing the impact of phylogenetic information in ecological meta-analysis
(Blackwell Publishing Ltd/CNRS, 2012)
Individual and combined effects of two types of phenological shifts on predator–prey interactions
(Ecological Society of America, 2016)
Timing of phenological events varies among years with natural variation in environmental conditions and is also shifting in response to climate change. These phenological shifts likely have many effects on species interactions. ...
Balancing anti-herbivore benefits and anti-pollinator costs of defensive mutualists
(Ecological Society of America, 2014)
Quantifying costs and benefits of ostensibly mutualistic interactions is an important step toward understanding their evolutionary trajectories. In food-for-protection interactions between ants and extrafloral nectar ...