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dc.contributor.advisor Strassmann, Joan E.
dc.contributor.advisor Queller, David C.
dc.creatorSmith, Margaret Harris
dc.date.accessioned 2009-06-04T08:15:27Z
dc.date.available 2009-06-04T08:15:27Z
dc.date.issued 2004
dc.identifier.citation Smith, Margaret Harris. "Genotypic diversity and population structure in Dictyostelium discoideum." (2004) Master’s Thesis, Rice University. https://hdl.handle.net/1911/17730.
dc.identifier.urihttps://hdl.handle.net/1911/17730
dc.description.abstract Current population genetics literature presumes a lack of population structure in microorganisms due to their large population sizes, ubiquitous dispersal, and absence of geographic barriers. Contrary to this, we found evidence of great population subdivision in the social amoeba, Dictyostelium discoideum. Pairwise values of Fst and Rst were significant between samples collected from sites separated by distances from 100m--10,000km (P < 0.05 after sequential Bonferroni). Three- and two-level analyses of molecular variance (AMOVA) confirmed the existence of population structure (Fst 0.30, Rst = 0.48, P < 0.001 for three-level; Fst = 0.297, Rst = 0.474, P < 0.001 for two-level). Further, linearized pairwise Fst values were significantly correlated with natural logarithm of geographic distance (r = 0.471, P < 0.012) indicating isolation by distance. Genotypic diversity of populations remained moderate (Nei (1987) average gene diversity ∼0.50) in spite of the decreased population diversity expected with such Fst and Rst values.
dc.format.extent 20 p.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.subjectMolecular biology
Genetics
dc.title Genotypic diversity and population structure in Dictyostelium discoideum
dc.type.genre Thesis
dc.type.material Text
thesis.degree.department Ecology and Evolutionary Biology
thesis.degree.discipline Natural Sciences
thesis.degree.grantor Rice University
thesis.degree.level Masters
thesis.degree.name Master of Arts


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