Now showing items 1-4 of 4

  • Chemical physics of protein folding 

    Wolynes, Peter G.; Eaton, William A.; Fersht, Alan R. (2012-10-30)
  • Frustration in biomolecules 

    Ferreiro, Diego U.; Komives, Elizabeth A.; Wolynes, Peter G. (2014)
    Biomolecules are the prime information processing elements of living matter. Most of these inanimate systems are polymers that compute their own structures and dynamics using as input seemingly random character strings of ...
  • Funneling and frustration in the energy landscapes of some designed and simplified proteins 

    Truong, Ha H.; Kim, Bobby L.; Schafer, Nicholas P.; Wolynes, Peter G. (2013)
    We explore the similarities and differences between the energy landscapes of proteins that have been selected by nature and those of some proteins designed by humans. Natural proteins have evolved to function as well as ...
  • Predictive energy landscapes for folding α-helical transmembrane proteins 

    Kim, Bobby L.; Schafer, Nicholas P.; Wolynes, Peter G. (2014)
    We explore the hypothesis that the folding landscapes of membrane proteins are funneled once the proteins' topology within the membrane is established. We extend a protein folding model, the associative memory, water-mediated, ...