Now showing items 1472-1491 of 1625

    • T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients 

      Tong, Yin; Li, Zhoufang; Zhang, Hua; Xia, Ligang; Zhang, Meng; Xu, Ying; Wang, Zhanhui; Deem, Michael W.; Sun, Xiaojuan; He, Jiankui (2016)
      Type 1 diabetes mellitus (T1D) is an immune-mediated disease. The autoreactive T cells in T1D patients attack and destroy their own pancreatic cells. In order to systematically investigate the potential autoreactive T cell ...
    • Tales from the crypt: a parasitoid manipulates the behaviour of its parasite host 

      Weinersmith, Kelly L.; Liu, Sean M.; Forbes, Andrew A.; Egan, Scott P. (2017)
      There are many examples of apparent manipulation of host phenotype by parasites, yet few examples of hypermanipulation—where a phenotype-manipulating parasite is itself manipulated by a parasite. Moreover, few studies ...
    • Targeting pancreatic cancer with magneto-fluorescent theranostic gold nanoshells 

      Chen, Wenxue; Ayala-Orozco, Ciceron; Biswal, Nrusingh C.; Perez-Torres, Carlos; Bartels, Marc; Bardhan, Rizia; Stinnet, Gary; Liu, Xian-De; Ji, Baoan; Deorukhkar, Amit; Brown, Lisa V.; Guha, Sushovan; Pautler, Robia G.; Krishnan, Sunil; Halas, Naomi J.; Joshi, Amit (2014)
      Aim: We report a magneto-fluorescent theranostic nanocomplex targeted to neutrophil gelatinase-associated lipocalin (NGAL) for imaging and therapy of pancreatic cancer. Materials & methods: Gold nanoshells resonant at 810 ...
    • A Technique to Increase Accessibility to Late-Stage Chick Embryos for In Ovo Manipulations 

      Spurlin, James III; Lwigale, Peter (2013)
      Background: During early development, avian embryos are easily accessible in ovo for transplantations and experimental perturbations. However, these qualities of the avian embryonic model rapidly wane shortly after embryonic ...
    • The Teichmüller Theory of Harmonic Maps 

      Wolf, Michael (1989)
    • Template–Framework Interactions in Tetraethylammonium-Directed Zeolite Synthesis 

      Schmidt, Joel E.; Fu, Donglong; Deem, Michael W.; Weckhuysen, Bert M. (2016)
      Zeolites, having widespread applications in chemical industries, are often synthesized using organic templates. These can be cost-prohibitive, motivating investigations into their role in promoting crystallization. Herein, ...
    • Tensegrity and motor-driven effective interactions in a model cytoskeleton 

      Wang, Shenshen; Wolynes, Peter G. (2012)
      Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential for development. We ...
    • Terahertz and Infrared Spectroscopy of Gated Large-Area Graphene 

      Ren, Lei; Zhang, Qi; Yao, Jun; Sun, Zhengzong; Kaneko, Ryosuke; Yan, Zheng; Nanot, Sébastien L.; Jin, Zhong; Kawayama, Iwao; Tonouchi, Masayoshi; Tour, James M.; Kono, Junichiro (2012)
      We have fabricated a centimeter-size single-layer graphene device with a gate electrode, which can modulate the transmission of terahertz and infrared waves. Using time-domain terahertz spectroscopy and Fourier-transform ...
    • Ternary CuIn7Se11: Towards Ultra-Thin Layered Photodetectors and Photovoltaic Devices 

      Lei, Sidong; Sobhani, Ali; Wen, Fangfang; George, Antony; Wang, Qizhong; Huang, Yihan; Dong, Pei; Li, Bo; Najmaei, Sina; Bellah, James; Gupta, Gautam; Mohite, Aditya D.; Ge, Liehui; Lou, Jun; Halas, Naomi J.; Vajtai, Robert; Ajayan, Pulickel (2014)
      2D materials have been widely studied over the past decade for their potential applications in electronics and optoelectronics. In these materials, elemental composition plays a critical role in defining their physical ...
    • Teslaphoresis of Carbon Nanotubes 

      Bornhoeft, Lindsey R.; Castillo, Aida C.; Smalley, Preston R.; Kittrell, Carter; James, Dustin K.; Brinson, Bruce E.; Rybolt, Thomas R.; Johnson, Bruce R.; Cherukuri, Tonya K.; Cherukuri, Paul (2016)
      This paper introduces Teslaphoresis, the directed motion and self-assembly of matter by a Tesla coil, and studies this electrokinetic phenomenon using single-walled carbon nanotubes (CNTs). Conventional directed self-assembly ...
    • TESTING DISK-LOCKING IN NGC 2264 

      Cauley, P. Wilson; Johns-Krull, Christopher M.; Hamilton, Catrina M.; Lockhart, Kelly (2012)
      We test analytic predictions from different models of magnetospheric accretion, which invoke disk-locking, using stellar and accretion parameters derived from models of low-resolution optical spectra of 36 T Tauri stars ...
    • Testing morphodynamic controls on the location and frequency of river avulsions on fans versus deltas: Huanghe (Yellow River), China 

      Ganti, Vamsi; Chu, Zhongxin; Lamb, Michael P.; Nittrouer, Jeffrey A.; Parker, Gary (2014)
      A mechanistic understanding of river avulsion location and frequency is needed to predict the growth of alluvial fans and deltas. The Huanghe, China, provides a rare opportunity to test emerging theories because its high ...
    • Testing the estimated hypothetical response of a major CME impact on Earth and its implications to space weather 

      Bala, Ramkumar; Reiff, Patricia; Russell, C.T. (2015)
      The high-speed coronal mass ejection (CME), ejected on 23 July 2012, observed by STEREO-A on the same day as the leading edge of the CME arrived at 1AU was unique both in respect to the observed plasma and magnetic structure ...
    • Testis specific histone 2B is associated with sperm chromatin dynamics and bull fertility-a pilot study 

      Kutchy, Naseer A; Velho, Ana; Menezes, Erika S B; Jacobsen, Marie; Thibaudeau, Giselle; Wills, Robert W; Moura, Arlindo; Kaya, Abdullah; Perkins, Andy; Memili, Erdogan (2017-08-01)
      Abstract Background Bull fertility is the degree of sperm’s ability to fertilize and activate the egg and support embryo development, and this is critical for herd reproductive ...
    • Tests of fixity of the Indo-Atlantic hot spots relative to Pacific hot spots 

      Koivisto, Emilia A.; Andrews, David L.; Gordon, Richard G. (2014)
      Rates of inter-hot spot motion have been debated for decades. Herein we present updated predictions for the tracks of the Tristan da Cunha, Réunion, and Iceland hot spots assuming them to be fixed relative to Pacific hot ...
    • TFEB regulates lysosomal proteostasis 

      Song, Wensi; Wang, Fan; Savini, Marzia; Ake, Ashley; di Ronza, Alberto; Sardiello, Marco; Segatori, Laura (2013)
      Loss-of-function diseases are often caused by destabilizing mutations that lead to protein misfolding and degradation. Modulating the innate protein homeostasis (proteostasis) capacity may lead to rescue of native folding ...
    • The charged inflaton and its gauge fields: preheating and initial conditions for reheating 

      Lozanov, Kaloian D.; Amin, Mustafa A. (2016)
      We calculate particle production during inflation and in the early stages of reheating after inflation in models with a charged scalar field coupled to Abelian and non-Abelian gauge fields. A detailed analysis of the power ...
    • The CMS Modular Track Finder boards, MTF6 and MTF7 

      Acosta, D.; Brown, G.; Carnes, A.; Carver, M.; Curry, D.; Di Giovanni, G.P.; Furic, I.; Kropivnitskaya, A.; Madorsky, A.; Matveev, M.; Padley, P.; Rank, D.; Reeves, C.; Scurlock, B.; Wang, S. (2013)
      To accommodate the increase in energy and luminosity of the upgraded LHC, the CMS Endcap Muon Level 1 Trigger system has to be significantly modified. To provide the best track reconstruction, the Trigger system must now ...
    • The colonization and divergence patterns of Brandt’s vole (Lasiopodomys brandtii) populations reveal evidence of genetic surfing 

      Li, Ke; Kohn, Michael H.; Zhang, Songmei; Wan, Xinrong; Shi, Dazhao; Wang, Deng (2017)
      Background: The colonial habit of Brandt’s vole (Lasiopodomys brandtii) differs from that of most other species of the genus Microtus. The demographic history of this species and the patterns shaping its current genetic ...
    • The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins 

      Lohman, Jeremy R.; Ma, Ming; Cuff, Marianne E.; Bigelow, Lance; Bearden, Jessica; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N. Jr.; Shen, Ben (2014)
      Carrier proteins (CPs) play a critical role in the biosynthesis of various natural products, especially in nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymology, where the CPs are referred to as ...