Now showing items 1005-1024 of 1505

    • Quantitative Analysis of α-Synuclein Solubility in Living Cells Using Split GFP Complementation 

      Kothawala, Ahmed; Kilpatrick, Kiri; Novoa, Jose Andres; Segatori, Laura (2012)
      Presently incurable, Parkinson's disease (PD) is the most common neurodegenerative movement disorder and affects 1% of the population over 60 years of age. The hallmarks of PD pathogenesis are the loss of dopaminergic ...
    • Quantum effects and nonlocality in strongly coupled plasmonic nanowire dimers 

      Teperik, Tatiana V.; Nordlander, Peter; Aizpurua, Javier; Borisov, Andrei G. (2013)
      Using a fully quantum mechanical approach we study the optical response of a strongly coupled metallic nanowire dimer for variable separation widths of the junction between the nanowires. The translational invariance of ...
    • Quantum jumps via spontaneous Raman scattering 

      Hulet, Randall G.; Wineland, D.J. (1987)
      A single laser, which is used to induce and detect spontaneous Raman transitions, can be used to observe quantum jumps in a single atom. The population dynamics of a particular system, consisting of two S1/22 ground-state ...
    • Quantum mechanical effects in plasmonic structures with subnanometre gaps 

      Zhu, Wenqi; Esteban, Ruben; Borisov, Andrei G.; Baumberg, Jeremy J.; Nordlander, Peter; Lezec, Henri J.; Aizpurua, Javier; Crozier, Kenneth B. (2016)
      Metallic structures with nanogap features have proven highly effective as building blocks for plasmonic systems, as they can provide a wide tuning range of operating frequencies and large near-field enhancements. Recent ...
    • Quantum Phases of the Shastry-Sutherland Kondo Lattice: Implications for the Global Phase Diagram of Heavy-Fermion Metals 

      Pixley, J.H.; Yu, Rong; Si, Qimiao (2014)
      Considerable recent theoretical and experimental effort has been devoted to the study of quantum criticality and novel phases of antiferromagnetic heavy-fermion metals. In particular, quantum phase transitions have been ...
    • Quantum plasmonics: Symmetry-dependent plasmon-molecule coupling and quantized photoconductances 

      Song, Peng; Meng, Sheng; Nordlander, Peter; Gao, Shiwu (2012)
      We investigate photoinduced electron transport through nanoparticle dimers connected by linear and ringlike molecules. The two model junctions exhibit similar absorption but distinct photoconductance. The linear-chain junction ...
    • Quantum quench phase diagrams of an s-wave BCS-BEC condensate 

      Yuzbashyan, E.A.; Dzero, M.; Gurarie, V.; Foster, M.S. (2015)
      We study the dynamic response of an s-wave BCS-BEC (atomic-molecular) condensate to detuning quenches within the two-channel model beyond the weak-coupling BCS limit. At long times after the quench, the condensate ends up ...
    • QuantWorm: A Comprehensive Software Package for Caenorhabditis elegans Phenotypic Assays 

      Jung, Sang-Kyu; Aleman-Meza, Boanerges; Riepe, Celeste; Zhong, Weiwei; Hendricks, Michael (2014)
      Phenotypic assays are crucial in genetics; however, traditional methods that rely on human observation are unsuitable for quantitative, large-scale experiments. Furthermore, there is an increasing need for comprehensive ...
    • Quasiparticle coupled cluster theory for pairing interactions 

      Henderson, Thomas M.; Scuseria, Gustavo E.; Dukelsky, Jorge; Signoracci, Angelo; Duguet, Thomas (2014)
      We present an extension of the pair coupled cluster doubles (p-CCD) method to quasiparticles and apply it to the attractive pairing Hamiltonian. Near the transition point where number symmetry gets spontaneously broken, ...
    • Quasispecies theory for evolution of modularity 

      Park, Jeong-Man; Niestemski, Liang Ren; Deem, Michael W. (2015)
      Biological systems are modular, and this modularity evolves over time and in different environments. A number of observations have been made of increased modularity in biological systems under increased environmental ...
    • Quench-Induced Floquet Topologicalᅠp-Wave Superfluids 

      Foster, Matthew S.; Gurarie, Victor; Dzero, Maxim; Yuzbashyan, Emil A. (2014)
      Ultracold atomic gases in two dimensions tuned close to a p-wave Feshbach resonance were expected to exhibit topological superfluidity, but these were found to be experimentally unstable. We show that one can induce a ...
    • Radiative Decay Rates in Hg+ from Observations of Quantum Jumps in a Single Ion 

      Itano, Wayne M.; Bergquist, J.C.; Hulet, Randall G.; Wineland, D.J. (1987)
      Radiative decay rates connecting the lowest four energy levels of Hg+198 have been derived solely from an analysis of the fluctuations (quantum jumps) of the laser-induced fluorescence of the 194-nm first resonance transition ...
    • Radiative lifetime of the 2P state of lithium 

      McAlexander, W.I.; Abraham, E.R.I.; Hulet, R.G. (1996)
      We determine the radial dipole moment between the 2S and 2P states of atomic lithium by analyzing the long-range vibrational eigenenergies of the singly excited diatomic molecule. The result can be expressed in terms of ...
    • Rampant Parasexuality Evolves in a Hospital Pathogen during Antibiotic Selection 

      Beabout, Kathryn; Hammerstrom, Troy G.; Wang, Tim T.; Bhatty, Minny; Christie, Peter J.; Saxer, Gerda; Shamoo, Yousif (2015)
      Horizontal gene transfer threatens the therapeutic success of antibiotics by facilitating the rapid dissemination of resistance alleles among bacterial species. The conjugative mobile element Tn916 provides an excellent ...
    • Random Insertion of mCherry Into VP3 Domain of Adeno- associated Virus Yields Fluorescent Capsids With no Loss of Infectivity 

      Judd, Justin; Wei, Fang; Nguyen, Peter Q.; Tartaglia, Lawrence J.; Agbandje-McKenna, Mavis; Silberg, Jonathan J.; Suh, Junghae (2012)
      Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid ...
    • Range-Separated Brueckner Coupled Cluster Doubles Theory 

      Shepherd, James J.; Henderson, Thomas M.; Scuseria, Gustavo E. (2014)
      We introduce a range-separation approximation to coupled cluster doubles (CCD) theory that successfully overcomes limitations of regular CCD when applied to the uniform electron gas. We combine the short-range ladder channel ...
    • RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization 

      Chu, Gina Chia-Yi; Zhau, Haiyen E.; Wang, Ruoxiang; Rogatko, André; Feng, Xu; Zayzafoon, Majd; Liu, Youhua; Farach-Carson, Mary C.; You, Sungyong; Kim, Jayoung; Freeman, Michael R.; Chung, Leland W.K. (2014)
      Prostate cancer (PCa) metastasis to bone is lethal and there is no adequate animal model to study the mechanisms underlying the metastatic process. Here we report that receptor activator of NF-κB ligand (RANKL) expressed ...
    • Rapid evolution of dispersal ability makes biological invasions faster and more variable 

      Ochocki, Brad M.; Miller, Tom E.X. (2017)
      Genetic variation in dispersal ability may result in the spatial sorting of alleles during range expansion. Recent theory suggests that spatial sorting can favour the rapid evolution of life history traits at expanding ...
    • Rapid Exploration of Configuration Space with Diffusion-Map-Directed Molecular Dynamics 

      Zheng, Wenwei; Rohrdanz, Mary A.; Clementi, Cecilia (2013)
      The gap between the time scale of interesting behavior in macromolecular systems and that which our computational resources can afford often limits molecular dynamics (MD) from understanding experimental results and ...
    • Rapid heteroatom transfer to arylmetals utilizing multifunctional reagent scaffolds 

      Gao, Hongyin; Zhou, Zhe; Kwon, Doo-Hyun; Coombs, James; Jones, Steven; Behnke, Nicole Erin; Ess, Daniel H.; Kürti, László (2016)
      Arylmetals are highly valuable carbon nucleophiles that are readily and inexpensively prepared from aryl halides or arenes and widely used on both laboratory and industrial scales to react directly with a wide range of ...