Now showing items 1137-1156 of 2210

• #### Modular knowledge systems accelerate human migration in asymmetric random environments ﻿

(2016)
Migration is a key mechanism for expansion of communities. In spatially heterogeneous environments, rapidly gaining knowledge about the local environment is key to the evolutionary success of a migrating population. For ...
• #### Modular, Multi-Input Transcriptional Logic Gating with Orthogonal LacI/GalR Family Chimeras ﻿

(2014)
In prokaryotes, the construction of synthetic, multi-input promoters is constrained by the number of transcription factors that can simultaneously regulate a single promoter. This fundamental engineering constraint is an ...
• #### Modularity enhances the rate of evolution in a rugged fitness landscape ﻿

(2015)
Biological systems are modular, and this modularity affects the evolution of biological systems over time and in different environments. We here develop a theory for the dynamics of evolution in a rugged, modular fitness ...
• #### Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma ﻿

(2018)
Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthesis. Understanding the metabolic reprogramming ...
• #### Modulated magnetism and anomalous electronic transport in Ce3Cu4As4O2 ﻿

(2016)
The complex magnetism and transport properties of tetragonal Ce3Cu4As4O2 were examined through neutron scattering and physical property measurements on polycrystalline samples. The lamellar structure consists of alternating ...
• #### Modulation of chorus intensity by ULF waves deep in the inner magnetosphere ﻿

(2016)
Previous studies have shown that chorus wave intensity can be modulated by Pc4-Pc5 compressional ULF waves. In this study, we present Van Allen Probes observation of ULF wave modulating chorus wave intensity, which occurred ...
• #### Modulation-Doped Multiple Quantum Wells of Aligned Single-Wall Carbon Nanotubes ﻿

(2017)
Heterojunctions, quantum wells, and superlattices with precise doping profiles are behind today's electronic and photonic devices based on III–V compound semiconductors such as GaAs. Currently, there is considerable interest ...

(2015)
• #### Molecular machines open cell membranes ﻿

(2017)
Beyond the more common chemical delivery strategies, several physical techniques are used to open the lipid bilayers of cellular membranes[1]. These include using electric[2] and magnetic[3] fields, temperature[4], ...
• #### Molecular mechanisms of the interhead coordination by interhead tension in cytoplasmic dyneins ﻿

(2018)
Cytoplasmic dyneins play a major role in retrograde cellular transport by moving vesicles and organelles along microtubule filaments. Dyneins are multidomain motor proteins with two heads that coordinate their motion via ...
• #### Molecular origin of the weak susceptibility of kinesin velocity to loads and its relation to the collective behavior of kinesins ﻿

(2017)
Motor proteins are active enzymatic molecules that support important cellular processes by transforming chemical energy into mechanical work. Although the structures and chemomechanical cycles of motor proteins have been ...
• #### Molecular Probe of Pairing in the BEC-BCS Crossover ﻿

(2005)
We have used optical molecular spectroscopy to probe the many-body state of paired L6i atoms near a broad Feshbach resonance. The optical probe projects pairs of atoms onto a vibrational level of an excited molecule. The ...
• #### Molecular recognition of DNA by ligands: Roughness and complexity of the free energy profile ﻿

(2013)
Understanding the molecular mechanism by which probes and chemotherapeutic agents bind to nucleic acids is a fundamental issue in modern drug design. From a computational perspective, valuable insights are gained by the ...
• #### Molecular search with conformational change: One-dimensional discrete-state stochastic model ﻿

(2018)
Molecular search phenomena are observed in a variety of chemical and biological systems. During the search, the participating particles frequently move in complex inhomogeneous environments with random transitions between ...
• #### Molecular stripping, targets and decoys as modulators of oscillations in the NF-κB/IκBα/DNA genetic network ﻿

(2016)
Eukaryotic transcription factors in the NF-κB family are central components of an extensive genetic network that activates cellular responses to inflammation and to a host of other external stressors. This network consists ...
• #### Motor proteins and molecular motors: how to operate machines at the nanoscale ﻿

(2013)
Several classes of biological molecules that transform chemical energy into mechanical work are known as motor proteins or molecular motors. These nanometer-sized machines operate in noisy stochastic isothermal environment, ...
• #### A Mott insulator continuously connected to iron pnictide superconductors ﻿

(2016)
Iron-based superconductivity develops near an antiferromagnetic order and out of a bad-metal normal state, which has been interpreted as originating from a proximate Mott transition. Whether an actual Mott insulator can ...
• #### Mott localization in a pure stripe antiferromagnet ${\mathrm{Rb}}_{1\ensuremath{-}\ensuremath{\delta}}{\mathrm{Fe}}_{1.5\ensuremath{-}\ensuremath{\sigma}}{\mathrm{S}}_{2}$ ﻿

(2015)
A combination of neutron diffraction and angle-resolved photoemission spectroscopy measurements on a pure antiferromagnetic stripe Rb1−δFe1.5−σS2 is reported. A neutron diffraction experiment on a powder sample shows that ...
• #### Mott localization in a pure stripe antiferromagnet Rb1−δFe1.5−σS2 ﻿

(2015)
A combination of neutron diffraction and angle-resolved photoemission spectroscopy measurements on a pure antiferromagnetic stripe Rb1−δFe1.5−σS2 is reported. A neutron diffraction experiment on a powder sample shows that ...
• #### MUC1 stimulates EGFR expression and function in endometrial cancer ﻿

(2016)
The current standard of care for endometrial cancer patients involves hysterectomy with adjuvant radiation and chemotherapy, with no effective treatment for advanced and metastatic disease. MUC1 is a large, heavily ...