THE STRUCTURE ELUCIDATION OF GERBERINOL AND THE TOTAL SYNTHESIS OF FURANOEREMOPHILANE
HALLS, TIMOTHY DONALD JOHN
Doctor of Philosophy
The structure of gerberinol, isolated from the Indian plant Gerbera lanuginosa, has been elucidated as 3,3'-methylenebis-(5-methyl-4-hydroxy-2H-1-benzopyran-2-one). Furanoeremophilane has been synthesized from the known ketone, 3,4,4a,5,6,7,8,8a(beta)-octahydro-4a(beta),5(beta)-dimethylnapthalene-2(1H)-one, using oxycyclopropane chemistry in the key sequence for the preparation of the 3-methylfuran moiety.