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dc.contributor.advisor Clark, John W., Jr.
dc.creatorBartels, Annemarie
dc.date.accessioned 2009-06-04T00:33:54Z
dc.date.available 2009-06-04T00:33:54Z
dc.date.issued 1994
dc.identifier.urihttps://hdl.handle.net/1911/13811
dc.description.abstract This study models the network interactions of five classes of neurons in the crayfish retina which support lateral inhibition and directional selectivity. The models approximate pulse responses and responses to drifting sinusoidal gratings in each cell type. Lateral inhibition is implemented by a shunting inhibitory feedback from lamina amacrine cells to the photoreceptor terminals. This mechanism determines the range of possible spatial and temporal frequencies of the synaptic input signals to the transmedullary and tangential cells. Tangential cells implement a delay and compare operation via competitive binding of GABA and ACh to ligand-gated membrane channels. The delay and compare operation can account for the directional selectivity which is observed experimentally in the tangential cells but not in any of the cells which form its input pathway. The models presented are nonlinear. They can reproduce the observed pulse responses over wide range of light intensities.
dc.format.extent 138 p.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.subjectBiomedical engineering
Neurosciences
Biophysics
Biology
Engineering
dc.title A model of lateral inhibition and directional selectivity in the crayfish compound eye
dc.type.genre Thesis
dc.type.material Text
thesis.degree.department Biology
thesis.degree.discipline Natural Sciences
thesis.degree.grantor Rice University
thesis.degree.level Masters
thesis.degree.name Master of Science
dc.identifier.citation Bartels, Annemarie. "A model of lateral inhibition and directional selectivity in the crayfish compound eye." (1994) Master’s Thesis, Rice University. https://hdl.handle.net/1911/13811.


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