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Engineering Escherichia coli for the production of polyketide-based platform chemicals
The current chemical industry produces a diverse array of industrial chemicals from a handful of highly reduced byproducts (termed "platform chemicals") derived from oil refining. However, petroleum is a non-renewable ...
Novel approaches for the production of fuels and chemicals in Escherichia coli
Volatility of oil prices along with major concerns about climate change, oil supply security and depleting reserves have sparked renewed interest in the production of biofuels and biochemicals. While the carbohydrate portion ...
Novel enzymes and pathways facilitating biological utilization of one carbon compounds
Although biological systems hold great potential for the sustainable production of fuels and chemicals from one-carbon (C1) feedstocks (1), their C1 utilization reactions rely on specific acceptor molecules, complex metabolic ...