Now showing items 1-3 of 3
Development of a High-Throughput 3D Tumor Model for Bone Sarcomas
Preclinical drug testing commonly relies on the use of two-dimensional (2D) cultures, which allow for rapid drug screening in vitro. However, 2D cultures are unable to capture the complexity of the native three-dimensional ...
Biodegradable Hydrogel Composites for Growth Factor and Stem Cell Delivery in Osteochondral Tissue Engineering
Cartilage has a limited endogenous ability for self-repair and current clinical treatments for damaged or diseased cartilage tissue are insufficient. Additionally, there is a biological and mechanical interplay between ...
Development of Injectable, Dual Thermally and Chemically Gelling Hydrogels for Craniofacial Bone Tissue Engineering
The objective of this work was to design a novel injectable hydrogel system capable of delivering osteoprogenitor cell populations for the minimally invasive regeneration of craniofacial bone. To this end, injectable and ...