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Improved Understanding of Apoptosis and Metabolism in Chinese Hamster Ovary Cell Culture
Mammalian cell culture has gained importance in biotechnology for the development of therapeutic and diagnostic agents. Among them, Chinese hamster ovary (CHO) cells are regarded as the mammalian cell "workhorse". The use ...
A Sequence-Based, Population Genetic Model of Regulatory Pathway Evolution
Complex phenotypes with genetic cause are understood through many processes, including regulatory pathways, but our evolutionary understanding of these critical structures is undermined by poor models which fail to preserve ...