Now showing items 1-6 of 6
The biophysics of intracellular transport driven by structurally-defined systems of motor proteins
The number of motor proteins attached to cellular cargos is widely believed to influence intracellular transport processes and may play a role in transport regulation. However, to date, investigating the biophysics of ...
Improved Understanding of Apoptosis and Metabolism in Chinese Hamster Ovary Cell Culture
Mammalian cell culture has gained importance in biotechnology for the development of therapeutic and diagnostic agents. Among them, Chinese hamster ovary (CHO) cells are regarded as the mammalian cell "workhorse". The use ...
Recovery of neuronal channel densities from calcium fluorescence
Neurons have the ability to dynamically adjust their own membrane channel densities to modulate the strength of communication with other neurons. This process is integral to such neuronal functions as spatial recognition ...
A Sequence-Based, Population Genetic Model of Regulatory Pathway Evolution
Complex phenotypes with genetic cause are understood through many processes, including regulatory pathways, but our evolutionary understanding of these critical structures is undermined by poor models which fail to preserve ...
Computational and Theoretical Analysis of Influenza Virus Evolution and Immune System Dynamics
Influenza causes annual global epidemics and severe morbidity and mortality. The influenza virus evolves to escape from immune system antibodies that bind to it. The immune system produces influenza virus specific antibodies ...
Paramagnetic particle assemblies as colloidal models for atomic and molecular systems
Colloidal particles are ideal models for studying the behavior of atomic and molecular systems. They resemble their atomic and molecular analogues in that their dynamics are driven by thermal energy and their equilibrium ...