Now showing items 1-5 of 5
Stochasticity and cell population heterogeneity in an artificial lac operon genetic network
The purpose of this work is two-fold: (1) to develop a novel mathematical and computational framework that incorporates the major sources of cell population heterogeneity and (2) to use this framework to demonstrate the ...
Elucidating the connection between cell population heterogeneity and genetic regulatory architecture in specific artificial networks
Understanding the expression patterns of simple, synthetic gene regulatory networks will not only shed light into the complexity of naturally occurring networks, but it will also provide a platform for expression control ...
The effects of process conditions on the char reactivity: The experimental studies and the mathematical modeling
The internal pore structure of chars derived from many bituminous and sub-bituminous coals can be best described by bi-modal pore size distribution. Their macropores, which account for nearly all the porosity, are ...
Design of artificial genetic networks to regulate the biosynthesis of polyhydroxyalkanoate copolymers with desirable structures
The design of artificial genetic networks constitutes a powerful tool to regulate cellular physiology. Simple regulatory structures comprised of a few interacting genes can be assembled to engineer desirable phenotypes and ...
Change in cell motility and metabolism following culture under low shear conditions
Recent studies suggest that the human immune system, and in particular lymphocyte function, may be suppressed during space flight. However, the mechanisms by which mechanical forces affect the function of immune cells are ...