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    Evidence-based biomaterials research

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    Author
    Zhang, Kai; Ma, Bin; Hu, Kaiyan; Yuan, Bo; Sun, Xin; More... Song, Xu; Tang, Zhonglan; Lin, Hai; Zhu, Xiangdong; Zheng, Yufeng; García, Andrés J.; Mikos, Antonios G.; Anderson, James M.; Zhang, Xingdong Less...
    Date
    2022
    Abstract
    The fast development of biomaterials science and engineering has generated significant number of studies and publications as well as tremendous amount of research data. A methodology is needed to translate such research data and results to validated scientific evidence. This article for the first time proposes the concept and methodology of evidence-based biomaterials research, which is to use evidence-based research approach represented by systematic reviews to generate evidence for answering scientific questions related to biomaterials. After briefly introducing the advancement of biomaterials since 1950s, the scientific and engineering nature of biomaterials are discussed along with the roadmap of biomaterials translation from basic research to commercialized medical products, and the needs of scientific evidence. Key information of the evidence-based approach such as its origination from evidence-based medicine, levels of evidence, systematic review and meta-analysis, differences between systematic and narrative reviews is then highlighted. Applications with a step-by-step procedure of conducting evidence-based biomaterials research, three examples of biomaterials research using evidence-based approach to generate scientific evidence, and opportunities and challenges of evidence-based biomaterials research are presented. With its notable impact on the practice of medicine, the evidence-based approach is also expected to make influential contributions to the biomaterials field.
    Citation
    Zhang, Kai, Ma, Bin, Hu, Kaiyan, et al.. "Evidence-based biomaterials research." Bioactive Materials, 15, (2022) Elsevier: 495-503. https://doi.org/10.1016/j.bioactmat.2022.04.014.
    Published Version
    https://doi.org/10.1016/j.bioactmat.2022.04.014
    Type
    Journal article
    Publisher
    Elsevier
    Citable link to this page
    https://hdl.handle.net/1911/112411
    Rights
    This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
    Link to License
    http://creativecommons.org/licenses/by-nc-nd/4.0/).
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    • Bioengineering Publications [684]
    • Chemical and Biomolecular Engineering Publications [288]
    • Faculty Publications [5504]

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    Home | FAQ | Contact Us | Privacy Notice | Accessibility Statement
    Managed by the Digital Scholarship Services at Fondren Library, Rice University
    Physical Address: 6100 Main Street, Houston, Texas 77005
    Mailing Address: MS-44, P.O.BOX 1892, Houston, Texas 77251-1892
    Site Map