Works related to coronaviruses that are authored by members of the Rice community.

Recent Submissions

  • Impact of COVID-19 on residency choice: A survey of New York City medical students 

    Lee, Kate E.; Lim, Francesca; Silver, Elisabeth R.; Faye, Adam S.; Hur, Chin (2021)
    Objectives: The Coronavirus disease 2019 (COVID-19) pandemic disrupted medical student education, particularly in New York City (NYC). We aimed to assess the impact of the COVID-19 pandemic on medical students’ residency choices. Methods: The authors conducted a cross-sectional survey of medical students in all years of study at four NYC medical ...
  • Role of miR-2392 in driving SARS-CoV-2 infection 

    McDonald, J. Tyson; Enguita, Francisco J.; Taylor, Deanne; Griffin, Robert J.; Priebe, Waldemar; (2021)
    MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provide an exciting avenue toward antiviral therapeutics. From patient transcriptomic data, we determined that a circulating miRNA, miR-2392, is directly involved with severe acute respiratory syndrome coronavirus ...
  • COVID-19 Vaccines: Current Conditions and Future Prospects 

    Zieneldien, Tarek; Kim, Janice; Cao, Jessica; Cao, Chuanhai (2021)
    It has been over a year since SARS-CoV-2 was first reported in December of 2019 in Wuhan, China. To curb the spread of the virus, many therapies and cures have been tested and developed, most notably mRNA and DNA vaccines. Federal health agencies (CDC, FDA) have approved emergency usage of these S gene-based vaccines with the intention of minimizing ...
  • Sterically confined rearrangements of SARS-CoV-2 Spike protein control cell invasion 

    Dodero-Rojas, Esteban; Onuchic, Jose N; Whitford, Paul Charles; Center for Theoretical Biological Physics (2021)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and transmission involves a series of processes that may be targeted by vaccines and therapeutics. During transmission, host cell invasion is controlled by a large-scale (200–300 Å) conformational change of the Spike protein. This conformational rearrangement leads to ...
  • Standardizing data reporting in the research community to enhance the utility of open data for SARS-CoV-2 wastewater surveillance 

    McClary-Gutierrez, Jill S.; Aanderud, Zachary T.; Al-faliti, Mitham; Duvallet, Claire; Gonzalez, Raul; (2021)
    SARS-CoV-2 RNA detection in wastewater is being rapidly developed and adopted as a public health monitoring tool worldwide. With wastewater surveillance programs being implemented across many different scales and by many different stakeholders, it is critical that data collected and shared are accompanied by an appropriate minimal amount of ...
  • Contact Tracing Apps: Lessons Learned on Privacy, Autonomy, and the Need for Detailed and Thoughtful Implementation 

    Hogan, Katie; Macedo, Briana; Macha, Venkata; Barman, Arko; Jiang, Xiaoqian; (2021)
    The global and national response to the COVID-19 pandemic has been inadequate due to a collective lack of preparation and a shortage of available tools for responding to a large-scale pandemic. By applying lessons learned to create better preventative methods and speedier interventions, the harm of a future pandemic may be dramatically reduced. One ...
  • Extubation Failure in Critically Ill COVID-19 Patients: Risk Factors and Impact on In-Hospital Mortality 

    Ionescu, Filip; Zimmer, Markie S.; Petrescu, Ioana; Castillo, Edward; Bozyk, Paul; (2021)
    Purpose:We sought to identify clinical factors that predict extubation failure (reintubation) and its prognostic implications in critically ill COVID-19 patients.Materials and Methods:Retrospective, multi-center cohort study of hospitalized COVID-19 patients. Multivariate competing risk models were employed to explore the rate of reintubation and its ...
  • Mounting antiscience aggression in the United States 

    Hotez, Peter J.; Center for Health and Biosciences, James A Baker III Institute for Public Policy (2021)
    There is a troubling new expansion of antiscience aggression in the United States. It's arising from far-right extremism, including some elected members of the US Congress and conservative news outlets that target prominent biological scientists fighting the COVID-19 pandemic.
  • Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain 

    Staquicini, Daniela I.; Tang, Fenny H. F.; Markosian, Christopher; Yao, Virginia J.; Staquicini, Fernanda I.; (2021)
    Development of effective vaccines against coronavirus disease 2019 (COVID-19) is a global imperative. Rapid immunization of the entire human population against a widespread, continually evolving, and highly pathogenic virus is an unprecedented challenge, and different vaccine approaches are being pursued. Engineered filamentous bacteriophage (phage) ...
  • Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity 

    McAndrews, Kathleen M.; Dowlatshahi, Dara P.; Dai, Jianli; Becker, Lisa M.; Hensel, Janine; (2020)
    Evaluation of potential immunity against the novel severe acute respiratory syndrome (SARS) coronavirus that emerged in 2019 (SARS-CoV-2) is essential for health, as well as social and economic recovery. Generation of antibody response to SARS-CoV-2 (seroconversion) may inform on acquired immunity from prior exposure, and antibodies against the ...
  • Observing the silent world under COVID-19 with a comprehensive impact analysis based on human mobility 

    Wang, Shaobin; Tong, Yun; Fan, Yupeng; Liu, Haimeng; Wu, Jun; (2021)
    Since spring 2020, the human world seems to be exceptionally silent due to mobility reduction caused by the COVID-19 pandemic. To better measure the real-time decline of human mobility and changes in socio-economic activities in a timely manner, we constructed a silent index (SI) based on Google’s mobility data. We systematically investigated the ...
  • How Do We See COVID-19? Visual Iconographies of Racial Contagion 

    Ostherr, Kirsten (2020)
    Contagion media have historically performed the dual functions of scientific and ideological persuasion, often deploying an iconography of racial contagion that combines these two functions. In efforts to halt the spread of the virus, health, science, and media organizations create visual imagery to teach the public to imagine we can see and therefore ...
  • Filipinx Care, Social Proximity, and Social Distance 

    Marte-Wood, Alden Sajor (2021)
  • The Impacts of COVID-19 on US Maternity Care Practices: A Followup Study 

    Gutschow, Kim; Davis-Floyd, Robbie (2021)
    This article extends the findings of a rapid response article researched in April 2020 to illustrate how providers’ practices and attitudes towards COVID-19 had shifted in response to better evidence, increased experience, and improved guidance on how SARS-CoV-2 and COVID-19 impacted maternity care in the US. This article is based on a review of ...
  • Birthing Between the “Traditional” and the “Modern”: DāĪ Practices and Childbearing Women’s Choices During COVID-19 in Pakistan 

    Ali, Inayat; Sadique, Salma; Ali, Shahbaz; Davis-Floyd, Robbie (2021)
    Pregnancy and birth are biological phenomena that carry heavy cultural overlays, and pregnant and birthing women need care and attention during both ordinary and extraordinary times. Most Pakistani pregnant women now go to doctors and hospitals for their perinatal care. Yet traditional community midwives, called DāĪ in the singular and Dāyūn in the ...
  • Natural tannin extracts supplementation for COVID-19 patients (TanCOVID): a structured summary of a study protocol for a randomized controlled trial 

    Molino, Silvia; Pisarevsky, Andrea; Mingorance, Fabiana Lopez; Vega, Patricia; Stefanolo, Juan Pablo; (2021)
    This research aims to study the efficacy of tannins co-supplementation on disease duration, severity and clinical symptoms, microbiota composition and inflammatory mediators in SARS-CoV2 patients.
  • Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice 

    Huang, Kun; Zhang, Yufei; Hui, Xianfeng; Zhao, Ya; Gong, Wenxiao; (2021)
    Background: An ideal animal model to study SARS-coronavirus 2 (SARS-CoV-2) pathogenesis and evaluate therapies and vaccines should reproduce SARS-CoV-2 infection and recapitulate lung disease like those seen in humans. The angiotensin-converting enzyme 2 (ACE2) is a functional receptor for SARS-CoV-2, but mice are resistant to the infection because ...
  • Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity 

    Hoffmann, Markus; Hofmann-Winkler, Heike; Smith, Joan C.; Krüger, Nadine; Arora, Prerna; (2021)
    Background: Antivirals are needed to combat the COVID-19 pandemic, which is caused by SARS-CoV-2. The clinically-proven protease inhibitor Camostat mesylate inhibits SARS-CoV-2 infection by blocking the virus-activating host cell protease TMPRSS2. However, antiviral activity of Camostat mesylate metabolites and potential viral resistance have not ...
  • News Sentiment Informed Time-series Analyzing AI (SITALA) to curb the spread of COVID-19 in Houston 

    Desai, Prathamesh S. (2021)
    Coronavirus disease (COVID-19) has evolved into a pandemic with many unknowns. Houston, located in the Harris County of Texas, is becoming the next hotspot of this pandemic. With a severe decline in international and inter-state travel, a model at the county level is needed as opposed to the state or country level. Existing approaches have a few ...

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