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dc.creatorNicolaou, Kyriacos C.; Lu, Min; Mandal, Debashis; Gangwar, Sanjeev; Chowdari, Naidu S.; Poudel, Yam B.
dc.date.accessioned 2019-06-19T19:43:31Z
dc.date.available 2019-06-19T19:43:31Z
dc.date.issued 2019-03-19
dc.identifier.citation Nicolaou, Kyriacos C.; Lu, Min; Mandal, Debashis; Gangwar, Sanjeev; Chowdari, Naidu S.; Poudel, Yam B., "Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents." Patent US10233192B2. issued 2019-03-19. Retrieved from http://hdl.handle.net/1911/106108.
dc.identifier.urihttp://hdl.handle.net/1911/106108
dc.description.abstract In one aspect, the present disclosure provides new analogs of uncialamycin. The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates which may be used to treat cancer or another disease or disorder.
dc.format.extent 104
dc.language.iso eng
dc.title Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents
dc.type Utility patent
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes
dc.contributor.publisher United States Patent and Trademark Office
dc.type.genre patents
dc.type.dcmi Text
dc.date.filed 2017-08-15
dc.identifier.patentID US10233192B2
dc.contributor.assignee Rice University
dc.contributor.assignee The Scripps Research Institute
dc.contributor.assignee Bristol-Myers Squibb Company


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