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An Interior-Point Gradient Method for Large-Scale Totally Nonnegative Least Squares Problems
We study an interior-point gradient method for solving a class of so-called totally nonnegative least squares problems. At each iteration, the method decreases the residual norm along a diagonally scaled negative gradient ...
A Geometric Approach to Fluence Map Optimization in IMRT Cancer Treatment Planning
Intensity-modulated radiation therapy (IMRT) is a state-of-the-art technique for administering radiation to cancer patients. The goal of a treatment is to deliver a prescribed amount of radiation to the tumor, while limiting ...