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    • Developing stimulus-responsive adeno-associated virus vectors for cancer-targeted gene therapy 

      Evans, Annicka Carter (2018-12-10)
      The most significant challenge to current gene therapy trials is ensuring delivery to exclusively diseased sites. Both non-viral and viral vectors have broad natural tropisms that elicit off-target side effects when used as a treatment. Adeno-associated virus (AAV) has recently become the most commonly used vector for gene therapy trials because it ...